Linoleic acid is a fatty acid found in cell membrane lipids and most vegetable and nut oils. Onder some cellular conditions, linoleic acid is converted into leukotoxin and isoleukotoxin by a type of P450 enzymes, leading to numerous toxic effects. Along with other researchers, Professor Bruce Hammock from the Department of Entomology at the University of California, Davis has discovered that many of the toxic effects are actually due to the diols that form when the epoxides are hydrolyzed by an epoxide hydrolase enzyme. linoleic acid part a P450 enzyme part b он leukotoxin OH ow jsoleukotoxin part a expoxide hydrolase (EH) enzyme но OH но, leukotoxin diol но OH + 0 wd m HO, isoleukotoxin diol Draw the products you would expect when linoleic acid undergoes ozonolysis. 1. O3, -78°C CH3(CH2)4 (CH2),CO2H linoleic acid 2. S(CH3)2 mcl tarll slot
Linoleic acid is a fatty acid found in cell membrane lipids and most vegetable and nut oils. Onder some cellular conditions, linoleic acid is converted into leukotoxin and isoleukotoxin by a type of P450 enzymes, leading to numerous toxic effects. Along with other researchers, Professor Bruce Hammock from the Department of Entomology at the University of California, Davis has discovered that many of the toxic effects are actually due to the diols that form when the epoxides are hydrolyzed by an epoxide hydrolase enzyme. linoleic acid part a P450 enzyme part b он leukotoxin OH ow jsoleukotoxin part a expoxide hydrolase (EH) enzyme но OH но, leukotoxin diol но OH + 0 wd m HO, isoleukotoxin diol Draw the products you would expect when linoleic acid undergoes ozonolysis. 1. O3, -78°C CH3(CH2)4 (CH2),CO2H linoleic acid 2. S(CH3)2 mcl tarll slot
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:Linoleic acid is a fatty acid found in cell membrane lipids and most vegetable and nut oils.
Onder some cellular conditions, linoleic acid is converted into leukotoxin and isoleukotoxin by a type
of P450 enzymes, leading to numerous toxic effects. Along with other researchers, Professor Bruce
Hammock from the Department of Entomology at the University of California, Davis has discovered
that many of the toxic effects are actually due to the diols that form when the epoxides are
hydrolyzed by an epoxide hydrolase enzyme.
linoleic acid
part a
P450
enzyme
part b
он
leukotoxin
OH ow
jsoleukotoxin
part a
expoxide hydrolase
(EH) enzyme
но
OH
но,
leukotoxin diol
но
OH +
0 wd m
HO,
isoleukotoxin diol
Draw the products you would expect when linoleic acid undergoes ozonolysis.
1. O3, -78°C
CH3(CH2)4
(CH2),CO2H
linoleic acid
2. S(CH3)2
mcl tarll slot
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