Label all of the acidic hydrogen. (Do not count any of the ones that are not shown) Circle the one that is the most acidic Explain, using CARDIO, why it is the most acidic. H H H CI Monst 30091922sib was boe vlingul ogato bre moltarmo H 28057 enims WH basit bnd) WH Uns 2500 onordal

Chemistry
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Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
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Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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**Instructions:**

1. **Label all of the acidic hydrogen atoms.**
   - Note: Do not count any hydrogen atoms that are not shown.

2. **Circle the one that is the most acidic.**

3. **Explain, using CARDIO, why it is the most acidic.**

**Structure Analysis:**

- The chemical structure in the image is a complex organic molecule with a benzene ring and various functional groups attached.
  
- **CARDIO Explanation:**

  - **Charge:** Look at the ability of the atom to stabilize a negative charge.
  - **Atom:** Consider the atom to which the hydrogen is attached (electronegativity and size matter).
  - **Resonance:** Examine if the conjugate base can be stabilized through resonance.
  - **Dipole Induction:** Assess if the electronegativity of nearby atoms affects acidity through induction.
  - **Orbital:** Consider the orbital where the negative charge is located for hybridization effects (sp > sp2 > sp3 in acidity).

- **Functional Groups Identified:**
  - Hydrocarbons
  - Carbonyl groups
  - Amine group
  - Thiol group

Use the CARDIO criteria to determine which hydrogen is most acidic based on these structural features.
Transcribed Image Text:**Instructions:** 1. **Label all of the acidic hydrogen atoms.** - Note: Do not count any hydrogen atoms that are not shown. 2. **Circle the one that is the most acidic.** 3. **Explain, using CARDIO, why it is the most acidic.** **Structure Analysis:** - The chemical structure in the image is a complex organic molecule with a benzene ring and various functional groups attached. - **CARDIO Explanation:** - **Charge:** Look at the ability of the atom to stabilize a negative charge. - **Atom:** Consider the atom to which the hydrogen is attached (electronegativity and size matter). - **Resonance:** Examine if the conjugate base can be stabilized through resonance. - **Dipole Induction:** Assess if the electronegativity of nearby atoms affects acidity through induction. - **Orbital:** Consider the orbital where the negative charge is located for hybridization effects (sp > sp2 > sp3 in acidity). - **Functional Groups Identified:** - Hydrocarbons - Carbonyl groups - Amine group - Thiol group Use the CARDIO criteria to determine which hydrogen is most acidic based on these structural features.
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