Kidney in Diabetes Many disease processes affect the kidney, including diabetes. The characteristic pattern of the diabetic kidney is glomerulosclerosis. Among the glomerular capillaries in a renal corpuscle yoL should be able to see round clear pink masses characteristic of glomerulosclerosis. As the disease progresses the sclerotic nodules eplarge and eventually compress and engulf the capillaries, obliterating the glomerular tuft. How does this lead to kidney failure?

Human Anatomy & Physiology (11th Edition)
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ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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**LABORATORY SIMULATION FOR RENAL SYSTEM PHYSIOLOGY**

**PhysioEx Program on Computer:**

Know the information on the renal system, and answer all the questions on handouts.

---

**Kidney in Diabetes**

Many disease processes affect the kidney, including diabetes. The characteristic pattern of the diabetic kidney is glomerulosclerosis. Among the glomerular capillaries in a renal corpuscle you should be able to see round clear pink masses characteristic of glomerulosclerosis. As the disease progresses, the sclerotic nodules enlarge and eventually compress and engulf the capillaries, obliterating the glomerular tuft.

**How does this lead to kidney failure?**

* * * 

* * *

---

**Chronic Pyelonephritis**

Pyelonephritis is initially a disease of the tubules. In later stages, the glomeruli may be affected. The colloidal areas are actually collagen and obviously collagen filled tubules are nonfunctional. Urinary tract infection is the usual cause of pyelonephritis.

**Why are diabetics prone to pyelonephritis?**

* * *

* * *
Transcribed Image Text:**LABORATORY SIMULATION FOR RENAL SYSTEM PHYSIOLOGY** **PhysioEx Program on Computer:** Know the information on the renal system, and answer all the questions on handouts. --- **Kidney in Diabetes** Many disease processes affect the kidney, including diabetes. The characteristic pattern of the diabetic kidney is glomerulosclerosis. Among the glomerular capillaries in a renal corpuscle you should be able to see round clear pink masses characteristic of glomerulosclerosis. As the disease progresses, the sclerotic nodules enlarge and eventually compress and engulf the capillaries, obliterating the glomerular tuft. **How does this lead to kidney failure?** * * * * * * --- **Chronic Pyelonephritis** Pyelonephritis is initially a disease of the tubules. In later stages, the glomeruli may be affected. The colloidal areas are actually collagen and obviously collagen filled tubules are nonfunctional. Urinary tract infection is the usual cause of pyelonephritis. **Why are diabetics prone to pyelonephritis?** * * * * * *
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KIDNEY FUNCTIONING:-

The function of the kidney is to remove and filter the waste products and fluids which are in excess and not of any use for the body, this all is expelled through the urine which is almost 2 quarts by filtering approximately 150 quarts of blood.

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