Ivermectin is being vaunted as a cure for covid-19. Is it a primary or secondary metabolite? Discuss its origin, manufacture, use, and contraindications. Show its chemical structure.
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- What are the limitations of Etelcalcetide, and how can the structure of the drug be modified to address these limitations?What is DEA number ? why we use this number in the prescription? what is the importance of DEA number?How was thermal stability measured in this paper and describe how GRL-1720 and 5h affect the thermal stability of Mpro and which drug has the larger effect? https://www.nature.com/articles/s41467-021-20900-6
- Name three reasons why a drug has different dosage forms.Which of the following is incorrect about blood glucose test interpretation A) fasting plasma glucose 6.1-6.8 defined as having IGT and should probably be screened again after a year or so. B) 2 results>7mmmol/l defined as having diabetes C) fasting plasma glucose >6mmol, recall for further test. D) fasting or random plasma glucose, on one reading of <11.1mmol/l is diagnostic of diabetesIn A Tabular form, Find the (A) innovator brands of these drugs, (B)leading brands in the Philippine market and the (C) taxonomical source of these drugs: Neostigmine Atropine Scopolamine Hyoscyamine Homatropine Ipratropium Tiotropium Clinidium Cyclopentolate Dicyclomine Eucatropine Benztropine Orphenadrine
- Describe in detail synthesis route (home-cooking recipe) of methamphetamine from pseudoephedrine. What supplies and ingredients are needed and where could one get these ingredients from? How easy would it be to synthesize methamphetamine in a home-made laboratory. Provide sources as well.Based on the USP XXII and NF XVIII, list the part of a monograph of the following: crude drug, natural product, and natural derivatives. The given question to me is: What is a pharmacopeial monograph? Based on the USP XXII and NF XVIII, list the part of a monograph of the following: crude drug, natural product, and natural derivatives.Despite the fact that many peptides have critical physiological functions(e.g., as hormones, neurotransmitters, antibacterial toxins), they are not considered to be ideal as drugs. The following questions illustrate some of the issues that limit the use of peptides as therapeutics.(a) Insulin is a peptide therapeutic used to manage Type 1 diabetes, whichaffects more than 20 million people worldwide according to the International Diabetes Federation. A significant limitation to the broad distribution and use of insulin to treat Type 1 diabetes is the fact that it must be administered by injection rather than orally. Why is insulin administered by injection and not orally?(b) Many of the D-amino acids found in nature have been discovered inbacterially produced peptides that have antibiotic properties. Bacteriasecrete these peptides into their environments to kill competitor bacteriaand thereby gain a selective advantage. Given your answer to part (a) ofthis question, what potential…
- In 2-page worth of words (around 500), discuss CYCLAMATE's regulation, allowable levels, and what group of people are at high risk for the side effects of CYCLAMATE in the body.b) Relate these advantages to explain why radiopharmaceuticals are often used in the treatment of i) prostate cancer (brachytherapy) ii) thyroid cancer (iodine-131 treatment) [Suggested word count 2201What is the importance in glycosylation in rtPA in terms of its activity as a protein therapeutic?