is NH2 stays pronated at pH 1 for Proline in this amino acids chain??? what would be the NH2's charge of proline??? since my professor said that proline does not have a ionizable side chain, so would it be NH2 or NH2+ for a given amino acid At pH1, is it NH2-Pro-Leu-COOH??? or NH3-Pro-Leu-COOH?????

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is NH2 stays pronated at pH 1 for Proline in this amino acids chain??? what would be the NH2's charge of proline??? since my professor said that proline does not have a ionizable side chain, so would it be NH2 or NH2+ for a given amino acid

At pH1, is it NH2-Pro-Leu-COOH??? or NH3-Pro-Leu-COOH?????

### Amino Acid Charge Table and Structural Information

#### Charge Calculation Table

This table illustrates the net charge of several amino acids at different pH levels: pH 1, pH 7, and pH 14. Each amino acid is represented by its three-letter code.

- **pH 1**
  - NH2: 1
  - Cys: 1
  - Lys: 1
  - Asp: 0
  - Glu: 0
  - Pro: 0
  - Leu: 0
  - Arg: 1
  - His: 0
  - Gly: 0
  - COOH: 0

- **pH 7**
  - NH2: 0
  - Cys: 0
  - Lys: 1
  - Asp: -1
  - Glu: -1
  - Pro: 0
  - Leu: 0
  - Arg: 1
  - His: 0
  - Gly: 0
  - COOH: -1

- **pH 14**
  - NH2: -1
  - Cys: -1
  - Lys: 0
  - Asp: -1
  - Glu: -1
  - Pro: 0
  - Leu: 0
  - Arg: 0
  - His: -1
  - Gly: 0
  - COOH: -1

The net charge at each pH is calculated by summing the charges: 
- For pH 1: +2
- For pH 7: -1
- For pH 14: -6

#### Structural Diagram

The image also includes a structural formula, detailing the peptide bond formation:

- **Amide Group**: Consists of a nitrogen atom bonded to a carbon atom, and this carbon is double-bonded to an oxygen atom (O=C-NH).

- **Carboxyl Group**: Contains a carbon atom double-bonded to an oxygen atom and single-bonded to a hydroxyl group (COOH).

#### Amino Acid Sequence

The sequence listed vertically on the right side indicates:
"H2N-Cys-Lys-Asp-Glu-Pro-Leu-Arg-His-Gly" with their approximate
Transcribed Image Text:### Amino Acid Charge Table and Structural Information #### Charge Calculation Table This table illustrates the net charge of several amino acids at different pH levels: pH 1, pH 7, and pH 14. Each amino acid is represented by its three-letter code. - **pH 1** - NH2: 1 - Cys: 1 - Lys: 1 - Asp: 0 - Glu: 0 - Pro: 0 - Leu: 0 - Arg: 1 - His: 0 - Gly: 0 - COOH: 0 - **pH 7** - NH2: 0 - Cys: 0 - Lys: 1 - Asp: -1 - Glu: -1 - Pro: 0 - Leu: 0 - Arg: 1 - His: 0 - Gly: 0 - COOH: -1 - **pH 14** - NH2: -1 - Cys: -1 - Lys: 0 - Asp: -1 - Glu: -1 - Pro: 0 - Leu: 0 - Arg: 0 - His: -1 - Gly: 0 - COOH: -1 The net charge at each pH is calculated by summing the charges: - For pH 1: +2 - For pH 7: -1 - For pH 14: -6 #### Structural Diagram The image also includes a structural formula, detailing the peptide bond formation: - **Amide Group**: Consists of a nitrogen atom bonded to a carbon atom, and this carbon is double-bonded to an oxygen atom (O=C-NH). - **Carboxyl Group**: Contains a carbon atom double-bonded to an oxygen atom and single-bonded to a hydroxyl group (COOH). #### Amino Acid Sequence The sequence listed vertically on the right side indicates: "H2N-Cys-Lys-Asp-Glu-Pro-Leu-Arg-His-Gly" with their approximate
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