Investigators are trying to determine if the contamination of a town well led to significant increases in adverse health effects. During the period of time when water was consumed from this contaminated well, there were 16 birth defects among 414 births. After this well was shut off, there were 3 birth defects among 228 births. You asked to determine if the rate of birth defects was higher when the contaminated well was in use.  a. Test the claim that the contaminated well was not associated with a change in the rate of birth defects in the community at the alpha = 0.05 level, by using the two-proportion z test. Confirm your answers using Stata. b. Calculate a 95% confidence interval for the true difference between the proportions of birth defects when the contaminated well was in use versus when the well was shut down. c. Construct the 2x2 contingency table representing the data to Calculate the odds of a birth defect when the contaminated water was consumed and when the well was shut down.

MATLAB: An Introduction with Applications
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Author:Amos Gilat
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Chapter1: Starting With Matlab
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Investigators are trying to determine if the contamination of a town well led to significant increases in adverse health effects. During the period of time when water was consumed from this contaminated well, there were 16 birth defects among 414 births. After this well was shut off, there were 3 birth defects among 228 births. You asked to determine if the rate of birth defects was higher when the contaminated well was in use. 

a. Test the claim that the contaminated well was not associated with a change in the rate of birth defects in the community at the alpha = 0.05 level, by using the two-proportion z test. Confirm your answers using Stata.

b. Calculate a 95% confidence interval for the true difference between the proportions of birth defects when the contaminated well was in use versus when the well was shut down.

c. Construct the 2x2 contingency table representing the data to Calculate the odds of a birth defect when the contaminated water was consumed and when the well was shut down.

d. Calculate the ratio of these two estimates; this is the Odds Ratio and the log-odds-ratio. Include the standard error of the log odds ratio.

e. Construct and interpret the 90% confidence interval for the true odds ratio. 

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