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intestinal epithelial cells pump glucose into the cell against its concentration gradient using the Na*-glucose symporter. Recall hat the Na+ concentration is significantly higher outside the cell than inside the cell. The symporter couples the "downhill" ransport of two Na+ ions into the cell to the "uphill" transport of glucose into the cell. of the Nat concentration outside the cell ([Na* lout) is 141 mM and that inside the cell ([Na* lin) is 19.0 mM, and the cell potential is -52.0 mV (inside negative), calculate the maximum energy available for pumping a mole of glucose into the cell. Assume the temperature is 37 °C. AGgluc = 10.5 Incorrect kJ mol What is the maximum ratio of [glucose] in to [glucose]out that could theoretically be produced if the energy coupling were 100% efficient? 113

intestinal epithelial cells pump glucose into the cell against its concentration gradient using the Na*-glucose symporter. Recall hat the Na+ concentration is significantly higher outside the cell than inside the cell. The symporter couples the "downhill" ransport of two Na+ ions into the cell to the "uphill" transport of glucose into the cell. of the Nat concentration outside the cell ([Na* lout) is 141 mM and that inside the cell ([Na* lin) is 19.0 mM, and the cell potential is -52.0 mV (inside negative), calculate the maximum energy available for pumping a mole of glucose into the cell. Assume the temperature is 37 °C. AGgluc = 10.5 Incorrect kJ mol What is the maximum ratio of [glucose] in to [glucose]out that could theoretically be produced if the energy coupling were 100% efficient? 113

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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**Title: Energy Dynamics of Glucose Transport in Intestinal Epithelial Cells** **Overview:** Intestinal epithelial cells transport glucose against its concentration gradient using the Na<sup>+</sup>-glucose symporter. This mechanism utilizes the higher external concentration of Na<sup>+</sup> to facilitate the "uphill" transport of glucose into the cell, coupling it with the "downhill" transport of Na<sup>+</sup> ions. **Problem Statement:** Given: - \( \text{[Na}^+\text{]}_{\text{out}} = 141 \text{ mM} \) - \( \text{[Na}^+\text{]}_{\text{in}} = 19.0 \text{ mM} \) - Cell potential = \(-52.0 \, \text{mV} \) (inside negative) - Temperature = \( 37 \, \text{°C} \) Calculate the maximum energy available for pumping a mole of glucose into the cell. **Calculation Box:** - \( \Delta G_{\text{gluc}} = \) \(10.5 \, \text{kJ/mol} \) - *Status:* Incorrect **Question:** What is the maximum theoretical ratio of \([\text{glucose}]_{\text{in}}\) to \([\text{glucose}]_{\text{out}}\) assuming 100% energy coupling efficiency? **Options:** - ☐ 1.13 - ☐ 2700 - ☐ 7.90 - ☑ 3.7 × 10<sup>-4</sup> This illustrative scenario introduces students to key concepts in cellular transport mechanisms and thermodynamics, specifically focusing on the role of ion gradients in active transport.
Transcribed Image Text:**Title: Energy Dynamics of Glucose Transport in Intestinal Epithelial Cells** **Overview:** Intestinal epithelial cells transport glucose against its concentration gradient using the Na<sup>+</sup>-glucose symporter. This mechanism utilizes the higher external concentration of Na<sup>+</sup> to facilitate the "uphill" transport of glucose into the cell, coupling it with the "downhill" transport of Na<sup>+</sup> ions. **Problem Statement:** Given: - \( \text{[Na}^+\text{]}_{\text{out}} = 141 \text{ mM} \) - \( \text{[Na}^+\text{]}_{\text{in}} = 19.0 \text{ mM} \) - Cell potential = \(-52.0 \, \text{mV} \) (inside negative) - Temperature = \( 37 \, \text{°C} \) Calculate the maximum energy available for pumping a mole of glucose into the cell. **Calculation Box:** - \( \Delta G_{\text{gluc}} = \) \(10.5 \, \text{kJ/mol} \) - *Status:* Incorrect **Question:** What is the maximum theoretical ratio of \([\text{glucose}]_{\text{in}}\) to \([\text{glucose}]_{\text{out}}\) assuming 100% energy coupling efficiency? **Options:** - ☐ 1.13 - ☐ 2700 - ☐ 7.90 - ☑ 3.7 × 10<sup>-4</sup> This illustrative scenario introduces students to key concepts in cellular transport mechanisms and thermodynamics, specifically focusing on the role of ion gradients in active transport.
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