Please provide neat and clean handwriting and clear image Insulin does not enter the cell that it affects. Instead, it starts a signal cascade within the cell. The signal culminates with theregulation of insulin-sensitive cytosolic enzymes and the transcription of specific nuclear genes that regulate metabolism.Place the steps of the insulin signaling pathway that regulates gene transcription in the order in which they occur. Not all thesteps will be placed.Insulin binds its receptor.Transcription factors activate.Answer BankINSR autophosphorylates.Sos facilitates GDP release and GTP binding to Ras.Ras activates the first of three protein kinases in a series.Raf phosphorylates MEK, which activates ERK. A protein kinase enters the nucleus.INSR phosphorylates IRS1. PKB inactivates GSK3, thereby activating GS.Grb2 assists the interaction between IRS1 and Sos.PKA activates downstream cytosolic enzymes.INSR phosphorylates GRK.

Cell signaling is the way of communication of cells. It involves cascades of chemical reactions in…

Insulin does not enter the cell that it affects. Instead, it starts a signal cascade within the cell. The signal culminates with the regulation of insulin-sensitive cytosolic enzymes and the transcription of specific nuclear genes that regulate metabolism. Place the steps of the insulin signaling pathway that regulates gene transcription in the order in which they occur. Not all the steps will be placed.

Insulin does not enter the cell that it affects. Instead, it starts a signal cascade within the cell. The signal culminates with the regulation of insulin-sensitive cytosolic enzymes and the transcription of specific nuclear genes that regulate metabolism. Place the steps of the insulin signaling pathway that regulates gene transcription in the order in which they occur. Not all the steps will be placed.

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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