Don't use Ai.Answer in step by step with explanation. In Zero order elimination kineticsQuestion 5 options:A constant fraction of the drug is eliminatedA constant amount of the drug is eliminatedA constant fraction of the drug is bound to plasma proteinsA constant amount of the drug is bound to plasma proteins

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Answered: In Zero order elimination kinetics…

Basic Clinical Laboratory Techniques 6E

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ISBN:9781133893943

Author:ESTRIDGE

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Chapter3: Basic Hemostasis

Section3.4: Prothrombin Time

Problem 14RQ

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Variation Relationship: 1. Rate of elimination 2. duration of action increase in 1 will increase 2 increase in 1 will decrease 2 1 will not affect 2 Quantitative Comparison: Time of onset of action: 1. enteric-coated tablet vs. 2. capsule 1 is greater than 2 1 is less than 2 1 is equal to 2 A drug with a pka = 3 immersed in a medium with pH = 3 Amount of drug 1. ionized vs. 2. non-ionized 1 is greater than 2 1 is less than 2 1 is equal to 2
A single dose of 300mg of drug is 63% bioavailable by the IM route. The same drug is 42% bioavailable by the oral route. How many 150mg tablets would need to be administered PO BID to achieve plasma levels comparable to the IM dose?
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Mrs B, aged 43 years, weight 56 kg, requires a loading dose of drug B. The target plasma concentration is 18.9 mg/ L, volume of distribution is 0.5 L/ kg, the salt factor is 0.9 and bioavailability fraction is 1. What is the intravenous loading dose (LD) of Drug B in milligrams (mg)? units - mg LD = Cp desired x Vd S x F Where Cp desired is the target plasma concentration; Vd is the volume of distribution; S is the salt factor and F is the bioavailability fraction
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Order. Cefotan 1.2 g IM q12h. Available to you is a 2 g vial of Cefotan with the following instructions related to reconstitution. Approximate Withdrawable Volume Concentration (mg/mL) (mL) Vial Size Amount of Diluent Approximate Average added (mL) 1g 2.5 400 2g 500 How many mL should you administer for one dose? A 3 mL syringe will be used.
mL b) Order of Ex.12: Calculate the following injectable dosages. a) Order of dosage: Lasix 40 mg intramuscularly. Supply: Lasix 10 mg/mL Give: dosage: Atropine 0.4 mg intramuscularly one hour pre-operatively. Supply: Atropine 1/150 grain/mL (or 0.0067 grain/mL) Give: dosage: Valium 7.5 mg intramuscularly stat. Supply: Valium 10. mg/mL Give: _mL Ex.13: Use the given table to determine the following. 23.2 g ice mL c) Order of cm3 = g table salt 25.0 cm3 mL 102.2 g gold = g/mL mg/L Ex.14: A cube of metal has a mass of 14.6 g and its sides 3 = m3 density of ethanol = are 12.3 mm. What is the identity of this metal? cm
Order: Pantoprozole 40mg IV q12h. According to the IV drug guide, you need to add the 40mg /10mL dose to a 100 mL minibag of 0.9% NS for administration. The recommended rate of infusion is 30 minutes. If you administer the pantoprazole using an infusion pump, you need to set an hourly rate. In order to infuse the 100ml minibag in 30 minutes, what hourly rate would you set on the pump?

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In Zero order elimination kinetics Question 5 options: A constant fraction of the drug is eliminated A constant amount of the drug is eliminated A constant fraction of the drug is bound to plasma proteins A constant amount of the drug is bound to plasma proteins