In this pedigree: • The first tier (generation) are parents • The second tier (generation) are children • The third tier (generation) are grandchildren
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A: answer is A. Autosomal inheritance
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A. Which is the affected parent? Why is it the affected parent?
B. Is generation 2 dominant or recessive and Why? explanation?
C. Is generation 3 dominant or recessive? Why? explanation?
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- What are the genotypes of the mother and father in the pedigree below? The pedigree shows albinism (an autosomal recessive trait). The shaded shapes represent albino individuals. a. mother - homozygous dominant; father - homozygous dominant b. mother - heterozygous; father - homozygous recessive c. mother - homozygous recessive; father - heterozygous d. mother - heterozygous; father - heterozygous e. mother - homozygous dominant; father - homozygous recessive17. Parents Jacob and Emma have had two children, Samuel and Matthew. Baby Samuel died at the age of nine days. When baby Matthew has trouble feeding, his parents take him in to the doctor. He is diagnosed with Maple Syrup Urine Disease (MSUD), a life-threatening condition in which the patient is not able to break down proteins from 19 their food. As Matthew receives treatment, Jacob and Emma are referred to a genetic counselor. The genetic counselor collects information about their family. Neither of Jacob's parents were affected by MSUD. Jacob had one brother and three sisters. One of these sisters died shortly after birth. Similarly, neither of Emma's parents were affected by MSUD. Emma had four brothers, and two of these died shortly after birth. a. Given what you know about Jacob and Emma's family, construct a pedigree that includes all three generations.. Assuming no involvement of the Bombay phenotype(in case you’ve already read ahead to Section 3.2):a. If a girl has blood type O, what could be the genotypes and corresponding phenotypes of her parents?b. If a girl has blood type B and her mother has bloodtype A, what genotype(s) and correspondingphenotype(s) could the other parent have?c. If a girl has blood type AB and her mother is alsoAB, what are the genotype(s) and correspondingphenotype(s) of any male who could not be thegirl’s father?
- 15. The following pedigree shows inheritance of Huntington's disease, a fatal genetic disorder that causes neurodegeneration. Since signs and symptoms usually do not appear until adulthood, many who are carriers may not realize their risk of passing on the disease-causing allele. The following pedigree represents a family in which some people are affected by Huntington's disease. Reeessive Trit er btmnt be Mec yplicalty HinheteePurple Hair is dominant. Blue hair is recessive. One parent is heterozygous; the other parent has blue hair. A.) What is the probability of them having a blue-haired child?Doing genetic analysis it is determined that two parents are heterozygous for two separate unlinked recessive traits (i.e., both parents are heterozygous for both loci). Given this genetic information, what is the probability of their having a child which is homozygous recessive for both traits?
- Use the Punnett square to find the genotype of the missing parent. Having freckles is dominant (F) and having no freckles is recessive (). Curly hair is recessive (c) and straight hair is dominant (C). A man with curly hair marries a woman who is homozygous dominant for straight hair. Complete the Punnett square. What is the probability they will have a child with curly hair? Straight hair? FF Ff f Ff ff % curly % straightA. Identify the most likely inheritance pattern in the pedigree below. B. What are the genotypes of individuals II-2 and III-2? Use any letter for your example. 1 4 II 1 2 3 4 5 6 7 II 2 3 4 5 6 7 9 10 11 IV 1 2 3 6 7 8 2. 4,Suppose a woman who is a carrier (XNXN)marries a man who is colorblind (XnY). Is there any chance that they will have a male child with a normal color vision? What are the possible phenotypes? 大 A. No chance, 2 female carrier and 2 males colorblind B. Yes, 1 female carrier, 1 female color blind, 1 male with normal color vision and 1 male colorblind C. Yes, 1 female colorblind and 2 males with normal vision and 1 male colorblind D. Yes, 2 males with normal color vision and 2 females carrier
- A. Four babies are born in a hospital and are mixed up. Based on the blood type and hairline, match the baby to its parents. Type A blood and Type B blood are codominant and type O is recessive. Widow's peak is dominant to a straight hairline. Each baby has the following phenotypes: Baby A = B blood, widows peak Baby B = B blood, straight hairline Baby C=AB blood, straight hairline Baby D = O blood, straight hairline The phenotypes of the parents are as follows: Ms. Smith: A blood, widows peak Mr. Smith: B blood, straight hairline Ms. Jones: O blood, widows peak Mr. Jones: O blood, widows peak Ms. Black: AB blood, widows peak Mr. Black: O blood, straight hairline Ms. Green: B blood, straight hairline Mr. Green: B blood, straight hairline which the The parent cell bN T L/ M LABORATORY EXERCISES IN GENETICS of inheritance, indicate how many children of each sex are expected to express the trait by filling in the appropriate circles and squares. a Autosomal recessive trait b. Autosomal dominant trait c. X-linked dominant trait grandfather is colorblind. All Rod's other grandparents have normal color vision. Rod has three sisters-Aida, Lorna, and Fe, all with normal color vision. Rod's oldest sister, Aida, is married to a man with normal color vision; they have two children, a colorblind boy and a girl with normal color vision. 5. Rod is colorblind. His mother and father have normal vision, but his maternal a. Using correct symbols, draw a pedigree of Rod's family. b. What is the most likely mode of inheritance for color blindness in Rod's family? c. If Rod marries a woman who has no family history of color blindness, what is the probability that their first child will be a colorblind male? 60The chart below is showing 4 generations of a family that is affected by a hereditary disease. a. Is the disorder being tracked dominant or recessive? How do you know? b. There is only one possible genotype for person C. True or False? c. What are the possible genotypes for person A? d. What are the possible genotypes for person B?, e. If two people with the same genotypes as person C's spouse and person A's spouse had a child, what is the probability that the child will be affected by this genetic disorder? (draw a Punnett square using the correct genotypes to help you). % chance offspring will be affected % chance offspring will not be affected