In the reaction of a nitrile with a Grignard reagent, there are two steps: a) nucleophilic addition of the Grignard to form an imine ion and b) hydrolysis of the imine to form a ketone. Draw the intermediate and the final product in this reaction. Ignore inorganic byproducts. CH₂MgBr CH3O NO Edit Imine Ion Intermediate P
In the reaction of a nitrile with a Grignard reagent, there are two steps: a) nucleophilic addition of the Grignard to form an imine ion and b) hydrolysis of the imine to form a ketone. Draw the intermediate and the final product in this reaction. Ignore inorganic byproducts. CH₂MgBr CH3O NO Edit Imine Ion Intermediate P
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:In the reaction of a nitrile with a Grignard reagent, there are two
steps: a) nucleophilic addition of the Grignard to form an imine
ion and b) hydrolysis of the imine to form a ketone.
Draw the intermediate and the final product in this reaction.
Ignore inorganic byproducts.
N
CH3MgBr
CH3O
NO
Edit Imine Ion Intermediate
1. H₂O*
Q
Problem 25 c

Transcribed Image Text:NO
Edit Imine Ion Intermediate
CH3O
CH3O
1. H3O+
2. Neutralizing work-up
Edit Final Product
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