In the following reaction mechanism, what best describes the role of the Grignard reagent? +CH₂MgBr 1) ether 2) H3O* The Grignard reagent acts as a nucleophile and attacks the carbonyl carbon. The Grignard reagent acts as an electrophile and is attacked by the oxygen. The Grignard reagent is first protonated by the acid. The Grignard reagent acts as a nucleophile and removes a proton from the methyl group attached to the carbonyl carbon

Organic Chemistry
9th Edition
ISBN:9781305080485
Author:John E. McMurry
Publisher:John E. McMurry
Chapter20: Carboxylic Acids And Nitriles
Section20.SE: Something Extra
Problem 65AP: Identify the missing reagents a-f in the following scheme:
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In the following reaction mechanism, what best describes the role of the Grignard reagent?
0
+CH₂MgBr
1) ether
2) H3O*
The Grignard reagent acts as a nucleophile and attacks the carbonyl carbon.
The Grignard reagent acts as an electrophile and is attacked by the oxygen.
The Grignard reagent is first protonated by the acid.
The Grignard reagent acts as a nucleophile and removes a proton from the methyl
group attached to the carbonyl carbon.
Transcribed Image Text:In the following reaction mechanism, what best describes the role of the Grignard reagent? 0 +CH₂MgBr 1) ether 2) H3O* The Grignard reagent acts as a nucleophile and attacks the carbonyl carbon. The Grignard reagent acts as an electrophile and is attacked by the oxygen. The Grignard reagent is first protonated by the acid. The Grignard reagent acts as a nucleophile and removes a proton from the methyl group attached to the carbonyl carbon.
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