In the first steps of glycolysis, glucose is phosphorylated and converted to fructose-6-phosphate as shown. Answer the questions below that reference this reactions. 8 O=P -00 АТР ADP но но, но, Нехоkinase HO HO он но, D-glucose D-Glucose-6-phosphate O=P -0e Phosphoglucose isomerase но но, но HO., он HO OH D-Glucose-6-phosphate Fructose-6-phosphate a) Determine if the Phosphoglucose Isomerase reaction will proceed spontaneously towards the formation of products, reactants, or exist at equilibrium if the Keg = 0.5. Show or explain your answers for each. (D-glucose-6-phospate = G-6-P & D-fructose-6-phospate = F-6-P) a. [G-6-P] = 2.5 mM; [F-6-P] = 5 mM b. [G-6-P] = 5 mM; [F-6-P] = 2.5 mM c. [G-6-P] = 5 mM; [F-6-P] = 1 mM d. AG = -435 cal/mol
In the first steps of glycolysis, glucose is phosphorylated and converted to fructose-6-phosphate as shown. Answer the questions below that reference this reactions. 8 O=P -00 АТР ADP но но, но, Нехоkinase HO HO он но, D-glucose D-Glucose-6-phosphate O=P -0e Phosphoglucose isomerase но но, но HO., он HO OH D-Glucose-6-phosphate Fructose-6-phosphate a) Determine if the Phosphoglucose Isomerase reaction will proceed spontaneously towards the formation of products, reactants, or exist at equilibrium if the Keg = 0.5. Show or explain your answers for each. (D-glucose-6-phospate = G-6-P & D-fructose-6-phospate = F-6-P) a. [G-6-P] = 2.5 mM; [F-6-P] = 5 mM b. [G-6-P] = 5 mM; [F-6-P] = 2.5 mM c. [G-6-P] = 5 mM; [F-6-P] = 1 mM d. AG = -435 cal/mol
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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please help with 1 and 2, thank you.
![In the first steps of glycolysis, glucose is phosphorylated and converted to fructose-6-phosphate as
shown. Answer the questions below that reference this reactions.
O=P -00
OH
АТР
ADP
но,
но
Hexokinase
HO
HO,
HO
HO
D-glucose
D-Glucose-6-phosphate
8
O=P -0e
Phosphoglucose
isomerase
но
HO,.
"HO,
HO
"OH
но
OH
D-Glucose-6-phosphate
Fructose-6-phosphate
a) Determine if the Phosphoglucose Isomerase reaction will proceed spontaneously towards the
formation of products, reactants, or exist at equilibrium if the Keg = 0.5. Show or explain your
answers for each.
(D-glucose-6-phospate = G-6-P & D-fructose-6-phospate = F-6-P)
a. [G-6-P] = 2.5 mM; [F-6-P]= 5 mM
b. [G-6-P] = 5 mM; [F-6-P] = 2.5 mM
c. [G-6-P] = 5 mM; [F-6-P] = 1 mM
d. AG = -435 cal/mol
AG= 0 cal/mol
f. AG = 867 cal/mol
e.
b) What does the ratio of F-6-P/G-6-P have to be for the phospoglucose isomerase reaction to
spontaneously occur in the formation of D-Glucose-6-phosphate? Explain/show your answer.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F65d6007a-fe92-485c-9606-3db896e773b8%2Fc09c2822-80a3-4800-b682-4e7ef0d65a5c%2Fuca3cd_processed.png&w=3840&q=75)
Transcribed Image Text:In the first steps of glycolysis, glucose is phosphorylated and converted to fructose-6-phosphate as
shown. Answer the questions below that reference this reactions.
O=P -00
OH
АТР
ADP
но,
но
Hexokinase
HO
HO,
HO
HO
D-glucose
D-Glucose-6-phosphate
8
O=P -0e
Phosphoglucose
isomerase
но
HO,.
"HO,
HO
"OH
но
OH
D-Glucose-6-phosphate
Fructose-6-phosphate
a) Determine if the Phosphoglucose Isomerase reaction will proceed spontaneously towards the
formation of products, reactants, or exist at equilibrium if the Keg = 0.5. Show or explain your
answers for each.
(D-glucose-6-phospate = G-6-P & D-fructose-6-phospate = F-6-P)
a. [G-6-P] = 2.5 mM; [F-6-P]= 5 mM
b. [G-6-P] = 5 mM; [F-6-P] = 2.5 mM
c. [G-6-P] = 5 mM; [F-6-P] = 1 mM
d. AG = -435 cal/mol
AG= 0 cal/mol
f. AG = 867 cal/mol
e.
b) What does the ratio of F-6-P/G-6-P have to be for the phospoglucose isomerase reaction to
spontaneously occur in the formation of D-Glucose-6-phosphate? Explain/show your answer.
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