In questions 4-7, refer to the scheme below. Maxigesic is a combination analgesic containing acetaminophen (500 mg) and ibuprofen (150 mg) with a starch binder. Finish the flowchart to show how you could separate acetaminophen and ibuprofen using acid-base extractions. (Note: the pKa of ibuprofen is about 4.9 and the pKa of acetaminophen is 9.5). 4. Refer to letter A: Indicate the pH of a buffered aqueous solution that would selectively remove ibuprofen from the organic layer. 5. Refer to the funnel marked B: What compound is in the upper layer, and is it in an ionized or unionized form? 6. Refer to letter C: Indicate what solution is needed to cause the dissolved compound to precipitate, and identify the precipitate that forms. 7. Refer to letter D: Indicate what technique could be used to isolate the organic solid, and identify the solid that forms. ether Maxigesic tablet technique: B top layer OH A sBu pH range: он, NH bottom layer solution to add:
In questions 4-7, refer to the scheme below. Maxigesic is a combination analgesic containing acetaminophen (500 mg) and ibuprofen (150 mg) with a starch binder. Finish the flowchart to show how you could separate acetaminophen and ibuprofen using acid-base extractions. (Note: the pKa of ibuprofen is about 4.9 and the pKa of acetaminophen is 9.5). 4. Refer to letter A: Indicate the pH of a buffered aqueous solution that would selectively remove ibuprofen from the organic layer. 5. Refer to the funnel marked B: What compound is in the upper layer, and is it in an ionized or unionized form? 6. Refer to letter C: Indicate what solution is needed to cause the dissolved compound to precipitate, and identify the precipitate that forms. 7. Refer to letter D: Indicate what technique could be used to isolate the organic solid, and identify the solid that forms. ether Maxigesic tablet technique: B top layer OH A sBu pH range: он, NH bottom layer solution to add:
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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