In early 1960s, the National Cancer Institute was able to isolate a complex organic compound from the bark of the Pacific Yew, Taxus brevifolia. The structure of the cancer-fighting component of yew bark was determined in 1962, and the compound was names paclitaxel (Taxol). Taxol is an anticancer agent active against ovarian, breast, and some lung tumors. Given the structure of Taxol, identify and place an asterisk at the stereogenic or chirality centers present within its complex structures. (Hint: There are only 11 chirality centers). NH O OH Paclitaxel (Taxol) HO H OH

In early 1960s, the National Cancer Institute was able to isolate a complex organic compound from the bark of the Pacific Yew, Taxus brevifolia. The structure of the cancer-fighting component of yew bark was determined in 1962, and the compound was names paclitaxel (Taxol). Taxol is an anticancer agent active against ovarian, breast, and some lung tumors. Given the structure of Taxol, identify and place an asterisk at the stereogenic or chirality centers present within its complex structures. (Hint: There are only 11 chirality centers). NH O OH Paclitaxel (Taxol) HO H OH

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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