In 1979, bones found outside Ekaterinburg, Russia, were shown to bethose of Tsar Nicholas and his family, who were executed in 1918 by aBolshevik firing squad in the Russian Revolution. To prove that the skeletons were those of the royalfamily, mtDNA was extracted from the bone samples, amplified byPCR, and compared with mtDNA from living relatives of the tsar’sfamily.a. Why was DNA from the mitochondria analyzed instead of nuclearDNA? What are some of the advantages of using mtDNA for this type ofstudy?b. Mitochondrial DNA from which living relatives would provide usefulinformation for verifying that the skeletons were those of the royal family?
In 1979, bones found outside Ekaterinburg, Russia, were shown to bethose of Tsar Nicholas and his family, who were executed in 1918 by aBolshevik firing squad in the Russian Revolution. To prove that the skeletons were those of the royalfamily, mtDNA was extracted from the bone samples, amplified byPCR, and compared with mtDNA from living relatives of the tsar’sfamily.a. Why was DNA from the mitochondria analyzed instead of nuclearDNA? What are some of the advantages of using mtDNA for this type ofstudy?b. Mitochondrial DNA from which living relatives would provide usefulinformation for verifying that the skeletons were those of the royal family?
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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In 1979, bones found outside Ekaterinburg, Russia, were shown to be
those of Tsar Nicholas and his family, who were executed in 1918 by a
Bolshevik firing squad in the Russian Revolution. To prove that the skeletons were those of the royal
family, mtDNA was extracted from the bone samples, amplified by
PCR, and compared with mtDNA from living relatives of the tsar’s
family.
a. Why was DNA from the mitochondria analyzed instead of nuclear
DNA? What are some of the advantages of using mtDNA for this type of
study?
b. Mitochondrial DNA from which living relatives would provide useful
information for verifying that the skeletons were those of the royal family?
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