If you incubate a protein with a single beta sheet in solution at pH = 14, the beta sheet no longer forms. Please describe the specific interactions within a beta sheet that are affected by pH and how an increase in pH would disrupt beta sheet formation.

If you incubate a protein with a single beta sheet in solution at pH = 14, the beta sheet no longer forms. Please describe the specific interactions within a beta sheet that are affected by pH and how an increase in pH would disrupt beta sheet formation.

Biology (MindTap Course List)

11th Edition

ISBN:9781337392938

Author:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Publisher:Eldra Solomon, Charles Martin, Diana W. Martin, Linda R. Berg

Chapter3: The Chemistry Of Life: Organic Compounds

Section: Chapter Questions

Problem 9TYU: Which of the following levels of protein structure may be affected by hydrogen bonding? (a) primary...

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Concept explainers

Nucleotides

It is an organic molecule made up of three basic components- a nitrogenous base, phosphate,and pentose sugar. The nucleotides are important for metabolic reactions andthe formation of DNA (deoxyribonucleic acid) and RNA (ribonucleic acid).

Nucleic Acids

Nucleic acids are essential biomolecules present in prokaryotic and eukaryotic cells and viruses. They carry the genetic information for the synthesis of proteins and cellular replication. The nucleic acids are of two types: deoxyribonucleic acid (DNA) and ribonucleic acid (RNA). The structure of all proteins and ultimately every biomolecule and cellular component is a product of information encoded in the sequence of nucleic acids. Parts of a DNA molecule containing the information needed to synthesize a protein or an RNA are genes. Nucleic acids can store and transmit genetic information from one generation to the next, fundamental to any life form.

Question

If you incubate a protein with a single beta sheet in solution at pH = 14, the beta sheet no longer
forms. Please describe the specific interactions within a beta sheet that are affected by pH and
how an increase in pH would disrupt beta sheet formation.
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