if Therapeutic index increase,does it means that it cause higher death rate??

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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if Therapeutic index increase,does it means that it cause higher death rate??
LEAD DSCOVERY
OStructure Modifications to Increase Potency, Therapeutic Index, and ADME Properties
Nonclassical Isosteres
10. Azomethine
-ND
11. Pyridine
NO,
NR
12. Benzene
心44人
13. Ring equivalents
H;C
NH2
14. Spacer group
(CH,),-
15. Hydrogen
F D
H.
5 add notes
Transcribed Image Text:LEAD DSCOVERY OStructure Modifications to Increase Potency, Therapeutic Index, and ADME Properties Nonclassical Isosteres 10. Azomethine -ND 11. Pyridine NO, NR 12. Benzene 心44人 13. Ring equivalents H;C NH2 14. Spacer group (CH,),- 15. Hydrogen F D H. 5 add notes
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