If the imaginary replacement of either of two protons forms enantiomers, then those protons are said to be enantiotopic. The NMR is not a chiral probe, and it cannot distinguish between enantiotopic protons. They are seen to be “equivalent by NMR.” What other protons in cyclobutanol are enantiotopic?

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If the imaginary replacement of either of two protons forms enantiomers, then those protons are said to be enantiotopic. The NMR is not a chiral probe, and it cannot distinguish between enantiotopic protons. They are seen to be “equivalent by NMR.” What other protons in cyclobutanol are enantiotopic?

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The imaginary replacement of either of two protons forms enantiomers, the protons are said to be enantiotopic. The NMR cannot distinguish between enantiotopic proton and they are seen to be chemically equivalent in NMR.

Enantiotropic is defined as relationship between two groups in a molecule when one or other group were replaced will generate a chiral compound. The two possible compounds resulting from that replacement would be enantiomers.

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