If a pre-synaptic cell releases a large amount of excitatory neurotransmitter into the synaptic cleft, how will that affect the PSPs? Does that large release ensure that the postsynaptic cell will initiate an action potential, and what role does the axon hillock play in this process/decision?
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If a pre-synaptic cell releases a large amount of excitatory neurotransmitter into the synaptic cleft, how will that affect the PSPs? Does that large release ensure that the postsynaptic cell will initiate an action potential, and what role does the axon hillock play in this process/decision?
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- Do Excitatory Potentials (EPSPs) and Inhibitory Potentials (IPSPs) only come into play at the synapses due to the NT's that bind to receptors on post-synaptic cell? And if an action potential is fired in the post-synaptic cell will it propagate from node to node dependent of this concept or do EPSPs and IPSPs come into play at each section of the axon?When an impulse arrives at the synapse, the synaptic vesicles open and release neurotransmitters into the cleft within a thousandth of a second. Within another ten thousandth of a second, these molecules have diffused across the cleft and bound to receptor sites in the effector cell. In what two ways is transmission across a synapse terminated so that the neuron’s signal is concluded?If action potential propagation from one neuron to another neuron requires ACh release, what event at the synaptic cleft explains the need for action potentials to arrive at a high rate before the post-synaptic membrane achieves threshold? the lack of sodium voltage gated channels on the post-synaptic membrane O the rapid breakdown of ACh by ACHE at the synaptic cleft the slow release of ACh by the synaptic vessicles the slow movement of sodium through chemical gates Previous Next MacBook Air
- If an excitatory neurotransmitter binds to the post-synaptic neuron, what type of an event will that cause? What happens if the neurotransmitter is an inhimitory neurotransmitter? What type of ion will move into the post-synaptic neuron? What type of polarizing event will occur? and What happen at the axon hillock?The purpose of an action potential (AP) is to propagate a signal down the axon to the axon terminal. What happens once it reaches the axon terminal? Using the experiment showing recordings from the post-synaptic cell (endplate potentials), describe what happens when an AP reaches the axon terminal and subsequently transmits the signal to a neighboring cell. What does this tell us about chemical neurotransmission?Given the steps shown below, which of the following is the correct sequence for transmission at a chemical synapse? 1. neurotransmitter binds with receptor 2. sodium ions rush into neuron's cytoplasm 3. action potential depolarizes the presynaptic membrane 4. ion channel opens to allow particular ion to enter cell 5. synaptic vesicles release neurotransmitter into the synaptic cleft O 1, 2, 3, 4, 5 O 5, 1, 2, 4, 3 O 2, 3, 5, 4, 1 O4, 3, 1, 2, 5 O 3, 2, 5, 1, 4
- Which of the following statements about action potentials and information transmission in the synaptic cleft is FALSE? 1. Action potentials determine the amount of neurotransmitters that are released into the synaptic cleft 2.Action potentials ultimately result in more calcium leaving the target cell at the postsynaptic membrane 3. Action potentials determine the duration that neurotransmitters are released into the synaptic cleft 4. Action potentials ultimately result in more calcium entering the neuron at the axon terminalSynaptic transmission depends upon :- a-direct transmission of impulses from the presynaptic neuron to the postsynaptic neuronb- diffusion of neurotransmitters from synaptic knobs into the soma and dendrites of postsynaptic neuronsc- presence of voltage-gated Ca ++ channels in membrane of synaptic knobsd- presence of voltage-gated Ca ++ channels in the subsynaptic membraneI have stimulated a neuron with dopamine for a second followed by treating it with cocaine and calcium chelating agent (which chelates out all calcium from the system making them unavailable for function), what will be the effect of such impulse on generating an action potential in the post-synaptic neuron? Will it be different if I pretreat the set of nerve cells with cocaine and calcium chelating agent followed by stimulating the neuron with dopamine? Justify your answer with proper reasoning in brief.
- Arrange the events that occur during synaptic transmission. Use letters A-F to denote the correct sequence. Use the diagram on the right as a clue. Example: SENDING NEURON B 1. lon channel opens Synepto SYNAPSE 1. lon channel opens 2. Neurotransmitter is released into synaptic cleft SYNAPTIC CLEFT RECEVING HEURC4 Neurotransmitter 3. Vesicle fuses with plasma membrane Jon chennels Neurotransmtter Reseptor deurotranemitter brohen down and sa sd 4. Neurotransmitter binds to receptor BOns 前 命 5. Action potential arrives 6. lon channel closes the obeicos in the bo y belo M (A nBesides the standard post- and pre-synapse that exchange information, non neuronal cell types also play a role in synaptic transmission. One of those are called astrocytes and can form a tripartite synapse. Explain the roles of astrocytes in synaptic transmission.What effect would you expect an antagonist that targets the voltage sensing domain of perisynaptic calcium channels of an inhibitory interneuron have on the firing frequency of a finically active neuron that interneuron synapses onto? Explain in details