Identify the parts of the G protein shown in the image. GB C Ga O GDP Answer Bank B subunit y subunit fatty acid Which of the subunits, when activated, associates with adenylyl cyclase (adenylate cyclase) and enables it to assume a more catalytically active conformation? о Gpy Gy a subunit

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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**Identify the Parts of the G Protein**

This image represents the structural components of a G protein, highlighting its subunits and other associated components. Each part is color-coded and labeled with a placeholder for identification.

1. **Components:**
   - Beige represents the space where the **α subunit** is located.
   - Pink represents the space where the **GDP** is located.
   - Dark blue represents the space where the **β subunit** is located.
   - Green represents the space where the **γ subunit** is located.

**Answer Bank:**
- GDP
- γ subunit
- β subunit
- Fatty acid
- α subunit

**Question:**
Which of the subunits, when activated, associates with adenylyl cyclase (adenylate cyclase) and enables it to assume a more catalytically active conformation?

- Gβγ
- Gγ
- Gβ
- Gα

**Explanation:**
Upon activation, the **Gα** subunit associates with adenylyl cyclase. This interaction is essential for the enzyme to attain a conformation that enhances its catalytic activity.

**Note:**
Learners can use the answer bank to identify specific parts of the G protein model in the image.
Transcribed Image Text:**Identify the Parts of the G Protein** This image represents the structural components of a G protein, highlighting its subunits and other associated components. Each part is color-coded and labeled with a placeholder for identification. 1. **Components:** - Beige represents the space where the **α subunit** is located. - Pink represents the space where the **GDP** is located. - Dark blue represents the space where the **β subunit** is located. - Green represents the space where the **γ subunit** is located. **Answer Bank:** - GDP - γ subunit - β subunit - Fatty acid - α subunit **Question:** Which of the subunits, when activated, associates with adenylyl cyclase (adenylate cyclase) and enables it to assume a more catalytically active conformation? - Gβγ - Gγ - Gβ - Gα **Explanation:** Upon activation, the **Gα** subunit associates with adenylyl cyclase. This interaction is essential for the enzyme to attain a conformation that enhances its catalytic activity. **Note:** Learners can use the answer bank to identify specific parts of the G protein model in the image.
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