Identify the charge states for aspartic acid (Asp), leucine (Leu) and Lysine (Lys) at pH 1, 7 and 12. Then calculate the isoelectric point (pl).
Identify the charge states for aspartic acid (Asp), leucine (Leu) and Lysine (Lys) at pH 1, 7 and 12. Then calculate the isoelectric point (pl).
Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
Problem 1P
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Transcribed Image Text:Question 3 of 40
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O side-by-Side
Identify the charge states for aspartic acid (Asp), leucine
Step 3: Next, determine the ionization states of aspartic acid
(Leu) and Lysine (Lys) at pH 1, 7 and 12. Then calculate
at each pH. The pK, of the amine is 9.6, while the pK, of
the carboxylic acid is 1.88 and the pK, of the carboxylic
the isoelectric point (pl).
Strategy: First identify the sidechain on each amino acid.
acid in the side chain is 3.65.
Then determine whether the side chain is acidic, basic or
neutral. Determine whether each functional group is
charged or not at the pH indicated. Calculate the (pI) from
At pH 1,
the pK, values of the functional groups.
O the amine is charged, the carboxylic acids are neutral.
O the amine and the carboxylic acids are all neutral.
O the amine is neutral and the carboxylic acids
are charged.
O the amine and carboxylic acids are all charged.
At pH 7,
the amine and the carboxylic acids are all neutral:
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Transcribed Image Text:Check Answer
Question 3 of 40
O Side-by-Side
Identify the charge states for aspartic acid (Asp), leucine
(Leu) and Lysine (Lys) at pH 1, 7 and 12. Then calculate
At pH 7,
the isoelectric point (pl).
Strategy: First identify the sidechain on each amino acid.
Then determine whether the side chain is acidic, basic or
O the amine and the carboxylic acids are all neutral.
neutral. Determine whether each functional group is
the amine is charged, the carboxylic acids are neutral.
charged or not at the pH indicated. Calculate the (pI) from
O the amine and carboxylic acids are all charged.
the pK, values of the functional groups.
O the amine is neutral and the carboxylic acids
are charged.
At pH 12,
the amine is charged, the carboxylic acids are neutral.
O the amine and carboxylic acids are all charged.
O the amine is neutral and the carboxylic acids
are charged.
O the amine and the carboxylic acids are all neutral,
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