Identify the charge states for aspartic acid (Asp), leucine (Leu) and Lysine (Lys) at pH 1, 7 and 12. Then calculate the isoelectric point (pl).

Biochemistry
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ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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Question 3 of 40
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O side-by-Side
Identify the charge states for aspartic acid (Asp), leucine
Step 3: Next, determine the ionization states of aspartic acid
(Leu) and Lysine (Lys) at pH 1, 7 and 12. Then calculate
at each pH. The pK, of the amine is 9.6, while the pK, of
the carboxylic acid is 1.88 and the pK, of the carboxylic
the isoelectric point (pl).
Strategy: First identify the sidechain on each amino acid.
acid in the side chain is 3.65.
Then determine whether the side chain is acidic, basic or
neutral. Determine whether each functional group is
charged or not at the pH indicated. Calculate the (pI) from
At pH 1,
the pK, values of the functional groups.
O the amine is charged, the carboxylic acids are neutral.
O the amine and the carboxylic acids are all neutral.
O the amine is neutral and the carboxylic acids
are charged.
O the amine and carboxylic acids are all charged.
At pH 7,
the amine and the carboxylic acids are all neutral:
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Transcribed Image Text:Question 3 of 40 > O side-by-Side Identify the charge states for aspartic acid (Asp), leucine Step 3: Next, determine the ionization states of aspartic acid (Leu) and Lysine (Lys) at pH 1, 7 and 12. Then calculate at each pH. The pK, of the amine is 9.6, while the pK, of the carboxylic acid is 1.88 and the pK, of the carboxylic the isoelectric point (pl). Strategy: First identify the sidechain on each amino acid. acid in the side chain is 3.65. Then determine whether the side chain is acidic, basic or neutral. Determine whether each functional group is charged or not at the pH indicated. Calculate the (pI) from At pH 1, the pK, values of the functional groups. O the amine is charged, the carboxylic acids are neutral. O the amine and the carboxylic acids are all neutral. O the amine is neutral and the carboxylic acids are charged. O the amine and carboxylic acids are all charged. At pH 7, the amine and the carboxylic acids are all neutral: MacBook Pro Q Search Default Search %2$ 3 4 5 6 8 delete E R Y U F H. J C V M command option ... B. ト
Check Answer
Question 3 of 40
O Side-by-Side
Identify the charge states for aspartic acid (Asp), leucine
(Leu) and Lysine (Lys) at pH 1, 7 and 12. Then calculate
At pH 7,
the isoelectric point (pl).
Strategy: First identify the sidechain on each amino acid.
Then determine whether the side chain is acidic, basic or
O the amine and the carboxylic acids are all neutral.
neutral. Determine whether each functional group is
the amine is charged, the carboxylic acids are neutral.
charged or not at the pH indicated. Calculate the (pI) from
O the amine and carboxylic acids are all charged.
the pK, values of the functional groups.
O the amine is neutral and the carboxylic acids
are charged.
At pH 12,
the amine is charged, the carboxylic acids are neutral.
O the amine and carboxylic acids are all charged.
O the amine is neutral and the carboxylic acids
are charged.
O the amine and the carboxylic acids are all neutral,
MacBook Pro
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ト
Transcribed Image Text:Check Answer Question 3 of 40 O Side-by-Side Identify the charge states for aspartic acid (Asp), leucine (Leu) and Lysine (Lys) at pH 1, 7 and 12. Then calculate At pH 7, the isoelectric point (pl). Strategy: First identify the sidechain on each amino acid. Then determine whether the side chain is acidic, basic or O the amine and the carboxylic acids are all neutral. neutral. Determine whether each functional group is the amine is charged, the carboxylic acids are neutral. charged or not at the pH indicated. Calculate the (pI) from O the amine and carboxylic acids are all charged. the pK, values of the functional groups. O the amine is neutral and the carboxylic acids are charged. At pH 12, the amine is charged, the carboxylic acids are neutral. O the amine and carboxylic acids are all charged. O the amine is neutral and the carboxylic acids are charged. O the amine and the carboxylic acids are all neutral, MacBook Pro Q Search Default Search & 3 4 5 8 9 delete E R Y U { G J K retu C M command option .... P. V - O 0 O O ト
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