I. REGULATION OF METABOLIC PATHWAYS Indicate what will happen (increase, decrease or no effect) to the activity of the enzyme or rate of the metabolic pathway given the following conditions. In not more than two sentences, justify you answer. Be specific with your justification. ENZYME/ PATHWAY CONDITION 1. phosphofructokinase-1 high [citrate] 2. pyruvate dehydrogenase complex low [Pi]

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