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- Azithromycin suspension is to be administered 10mg per Kg once daily for 3 days. a. Calculate the correct daily dose in mg, for a 60 pound child. b. Calculate the correct daily dose in ml, if the azithromycin suspension is available as a100mg/5ml strength. 3. Calculate a single dose in milliliters, for a 45 pound child receiving tobramycin 1.5mg/Kg IV Q8H. Tobramycin is available in 10mg/ml vials.Do not include zeros at the end of decimal numbers. The problems and drug orders are presented for practice only, and actual prescribed dosages will vary according to a patien factors. Order: penicillin G potassium 2,000,000 units IM q.8h Supply: 5,000,000 units Directions: Reconstitute with 18.2 mL for 250,000 units/mL; 8.2 mL for 500,000 units/mL; 3.2 mL for 1,000,000 units/mL mL for units/mL Reconstitute with Give: mL A Moving to another question will save this response. Type here to search Esc F2 OE F4 • F5 H9 F6 DELL [ d P F10describe the aim, mechanism of action and pathophysiological explanation of Metformin and ramipril including guidelines. Identify one risk and identify the effectiveness of each medication. Patient: 62 male HbA1C test result (9%), type 2 diabetes, 15% cardiovascular risk. renal screen: eGFR 90ml/min/1.73m2 : microalbuminuria- 3.5mg/mmol Also describe the Aim, guidelines and physiology of the following therapies: exercise plan- 150min Aerobic and 60min resistance exercise/week smoking cessation, alcohol consumption plan and dietary plan
- Do not include zeros at the end of decimal numbers. The problems and drug orders are presented for practice only, and actual prescribed factors. ler 1 mL to two decimal places. Order: Vantin 200 mg p.o., q.12h Supply: Vantin 100 mg/5 mL After reconstitution, the vial contains 50 mL. Give: Moving to another question will save this response. Type here to search mOrder Meperidine (Demerol) 50mg IV q4h prn. Refer to the label below. How much will you draw up to administer per dose? Nop-Catel srg e re, NOC 0641-054-25 Ronly Meperidine HCI Injection, USP Ench ml contains meperidine hydracho ride 100 mg in Water for Injection Buered with acetic acisedum otate Ual L Do not ine If preoptated Store at e ( rn (See USP Controlled Reem Temperature). e See package |100 mg/mL (0 25 x1 ml Single Dose Vials FOR INTRAMUSCULAR, SUBCUTANEOUS OR SLOW INTRAVENOUS USE WWETWARDCes) SOLVE THE FOLLOWING PROBLEMS OF DOSE CALCULATION, SHOW THE CALCULATIONS FOR EACH OF THEY: 8. If nembutal is used to anesthetize patients at a dose of 0.09mg/g body weight and the concentration of the solution is 60mg/ml. How many mL are needed to anesthetize a 4 pound patient? 9. Atropine is given in doses of .5mg/kg. How much will a patient who weighs 3.5 lbs receive? 10. To anesthetize a patient, a 10 ml bottle of Ketamine is available at a concentration at 10% If the dose of Ketamine in cats is 15 mg/Kg and the patient weighs 4 pounds. Calculate a) Weight of the patient in Kg. b) mg of Ketamine needed to anesthetize the patient. c) Volume in ml of Ketamine. I
- 9 Ordered: magnesium sulfate 2.5 mL/ min IV infusion, for a patient with con- vulsions. Directions: Dilute 4 g in 250 mL of D3W. Read the label for mg/ mL and prepare 4 g. a 50 mL 50% MAGNESIUM EnchlL cortans megnesium sufata, hetarra so mg Mry NDC 0074-2168-03 Time Cra Entared cortain HyS0 andior NaCH pH 60 (S5 to 70 406 Osmni SULFATE Inj., USP 4 mEq Mg**/mL PHARMACY BULK PACKAGE NOT FOR DIRECT INFUSION For LV. or LM. use Iralie. "for preparing LV. itnisteres enly See asert for complete dosage information and prsper uae of this covtainer. Discard vial 4 beurs tar inital entry Asingery tough the viai ciosure shguld be made withasteris enpersing set or transter derice. travenous infusion sohutions. Usa of a syringe wth neede is not recommended. The sbove process shouid be carried out under a laminar flow hood using epte technique. Stare at controled room temperature 15 to 3C to Caor Transfer intividuai doses to WARNING: Must be dilutad for LV. wse. Federal USA aw prihits dapensing…Calculate the amount to dispense for each of the following orders. When more than one dosage strength is available, choose the most appropriate. 1. Ordered: Azithromycin 1 g po daily for 5 days On hand: Azithromycin 500 mg tabletsGive typed full explanation not written Order: Zofran 32mg Available: Ondansetron (Zofran) 40mg/20ml Label: dilute in 50 mL 0.9% NS and infuse over 15 minutes. a. what dose of zofran would be prepared for the patient? b. at what rate would you set the IV?
- Answer the following questions:1. If excipients do not have pharmacodynamic activity, how do excipients affect the performance of the drug product?2. What is meant by the rate-limiting step in drug bioavailability from a solid oral drug product?3. What is the usual rate-limiting step for a poorly soluble and highly permeable drug (BCS 2)?4. How could the manufacturing process affect drug product performance?5. Drug absorption involves at least three distinct steps: dissolution, permeation, and disposition during transit in GI (an additional step of drug disposition in the body is involved as well for bioavailability). How are these processes validated in vitro when the in vivo requirement for drug bioavailability is waived?6. What is meant by “sink” conditions?7. What physical or chemical properties of a drug substance are important in designing a drug for (a) oral administration or (b) parenteral administration?8. For a lipid-soluble drug that has very poor aqueous solubility, what…The order for a client is Robitussin syrup (guaifenesin) 15mL po q.i.d. How many ounces of Robitussin would the client have received by 10 pm if the first dose was administered at 8 am?In treating a 54 year old female patient, an oncologist selects the drug Temozolomide, an anti tumor agent used in the treatment of refractory astrocystoma (brain tumor). The drug is used for a 28-day regimen, during w/c the five days of treatment include Temozolomide at a once daily dose of 150mg/m2/day. The patients medical chart indicates that she measures 5 ft and weighs 117 lbs. The physician asks the pharmacist to determine the proper combination of available capsule in dosing the patient. The drugin capsules containing 5, 20, 100 and 250mg of Temozolomide. Question: What combination of capsules would provide the daily dose of this drug? Show your computation.