I need help with problem #4

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
icon
Related questions
Question
100%
I need help with problem #4, thank you!
**Organic Chemistry Synthesis Problems**

**Question 4:**
*Devise a forward synthesis given the retrosynthetic analysis, only using the starting materials given and employing only Suzuki reactions for C-C bond forming reactions.*

**Part a.**
Reaction Scheme:

\[ \text{Reaction 1:} \quad \text{Benzene with two methyl groups} + \text{Alkene with halide group} \leftrightarrow \text{Final product} \]

**Part b.**
Reaction Scheme:

\[ \text{Reaction 1:} \quad \text{Benzene ring with R group} + \text{Benzene ring with iodine} \leftrightarrow \text{Final product} \]

**Part c.**
Reaction Scheme:

\[ \text{Reaction 1:} \quad \text{Benzene ring with methoxy group} + \text{Alkyl halide containing Br} \leftrightarrow \text{Final product} \]

**Question 5:**
*Draw the starting materials you could use to synthesize the following organic molecules, using only the Heck reaction for C-C bond-forming reactions.*

**Part a.**
Reaction Scheme:

\[ \text{Starting materials:} \quad \text{Alkene with halide group and H} + \text{Benzonitrile derivative} \leftrightarrow \text{Final product (benzene ring with cyano group and alkene chain)} \]

**Part b.**
Reaction Scheme:

\[ \text{Starting materials:} \quad \text{Alkene with halide group and H} + \text{Ethyl ester derivative} \leftrightarrow \text{Final product (benzene ring with ester group and alkene chain)} \] 

Each part involves the selection of appropriate starting materials that adhere to the Suzuki and Heck reaction mechanisms for carbon-carbon bond formation.
Transcribed Image Text:**Organic Chemistry Synthesis Problems** **Question 4:** *Devise a forward synthesis given the retrosynthetic analysis, only using the starting materials given and employing only Suzuki reactions for C-C bond forming reactions.* **Part a.** Reaction Scheme: \[ \text{Reaction 1:} \quad \text{Benzene with two methyl groups} + \text{Alkene with halide group} \leftrightarrow \text{Final product} \] **Part b.** Reaction Scheme: \[ \text{Reaction 1:} \quad \text{Benzene ring with R group} + \text{Benzene ring with iodine} \leftrightarrow \text{Final product} \] **Part c.** Reaction Scheme: \[ \text{Reaction 1:} \quad \text{Benzene ring with methoxy group} + \text{Alkyl halide containing Br} \leftrightarrow \text{Final product} \] **Question 5:** *Draw the starting materials you could use to synthesize the following organic molecules, using only the Heck reaction for C-C bond-forming reactions.* **Part a.** Reaction Scheme: \[ \text{Starting materials:} \quad \text{Alkene with halide group and H} + \text{Benzonitrile derivative} \leftrightarrow \text{Final product (benzene ring with cyano group and alkene chain)} \] **Part b.** Reaction Scheme: \[ \text{Starting materials:} \quad \text{Alkene with halide group and H} + \text{Ethyl ester derivative} \leftrightarrow \text{Final product (benzene ring with ester group and alkene chain)} \] Each part involves the selection of appropriate starting materials that adhere to the Suzuki and Heck reaction mechanisms for carbon-carbon bond formation.
Expert Solution
steps

Step by step

Solved in 4 steps with 3 images

Blurred answer
Knowledge Booster
Green Chemistry
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.
Similar questions
  • SEE MORE QUESTIONS
Recommended textbooks for you
Chemistry
Chemistry
Chemistry
ISBN:
9781305957404
Author:
Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:
Cengage Learning
Chemistry
Chemistry
Chemistry
ISBN:
9781259911156
Author:
Raymond Chang Dr., Jason Overby Professor
Publisher:
McGraw-Hill Education
Principles of Instrumental Analysis
Principles of Instrumental Analysis
Chemistry
ISBN:
9781305577213
Author:
Douglas A. Skoog, F. James Holler, Stanley R. Crouch
Publisher:
Cengage Learning
Organic Chemistry
Organic Chemistry
Chemistry
ISBN:
9780078021558
Author:
Janice Gorzynski Smith Dr.
Publisher:
McGraw-Hill Education
Chemistry: Principles and Reactions
Chemistry: Principles and Reactions
Chemistry
ISBN:
9781305079373
Author:
William L. Masterton, Cecile N. Hurley
Publisher:
Cengage Learning
Elementary Principles of Chemical Processes, Bind…
Elementary Principles of Chemical Processes, Bind…
Chemistry
ISBN:
9781118431221
Author:
Richard M. Felder, Ronald W. Rousseau, Lisa G. Bullard
Publisher:
WILEY