Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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I need help with problem #4, thank you!
![**Organic Chemistry Synthesis Problems**
**Question 4:**
*Devise a forward synthesis given the retrosynthetic analysis, only using the starting materials given and employing only Suzuki reactions for C-C bond forming reactions.*
**Part a.**
Reaction Scheme:
\[ \text{Reaction 1:} \quad \text{Benzene with two methyl groups} + \text{Alkene with halide group} \leftrightarrow \text{Final product} \]
**Part b.**
Reaction Scheme:
\[ \text{Reaction 1:} \quad \text{Benzene ring with R group} + \text{Benzene ring with iodine} \leftrightarrow \text{Final product} \]
**Part c.**
Reaction Scheme:
\[ \text{Reaction 1:} \quad \text{Benzene ring with methoxy group} + \text{Alkyl halide containing Br} \leftrightarrow \text{Final product} \]
**Question 5:**
*Draw the starting materials you could use to synthesize the following organic molecules, using only the Heck reaction for C-C bond-forming reactions.*
**Part a.**
Reaction Scheme:
\[ \text{Starting materials:} \quad \text{Alkene with halide group and H} + \text{Benzonitrile derivative} \leftrightarrow \text{Final product (benzene ring with cyano group and alkene chain)} \]
**Part b.**
Reaction Scheme:
\[ \text{Starting materials:} \quad \text{Alkene with halide group and H} + \text{Ethyl ester derivative} \leftrightarrow \text{Final product (benzene ring with ester group and alkene chain)} \]
Each part involves the selection of appropriate starting materials that adhere to the Suzuki and Heck reaction mechanisms for carbon-carbon bond formation.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F1e3e2134-96fc-4452-a677-73870439788a%2Fd01bb7ef-e60a-4777-bca7-62c9dff99ecb%2Fxlo8x7u_processed.jpeg&w=3840&q=75)
Transcribed Image Text:**Organic Chemistry Synthesis Problems**
**Question 4:**
*Devise a forward synthesis given the retrosynthetic analysis, only using the starting materials given and employing only Suzuki reactions for C-C bond forming reactions.*
**Part a.**
Reaction Scheme:
\[ \text{Reaction 1:} \quad \text{Benzene with two methyl groups} + \text{Alkene with halide group} \leftrightarrow \text{Final product} \]
**Part b.**
Reaction Scheme:
\[ \text{Reaction 1:} \quad \text{Benzene ring with R group} + \text{Benzene ring with iodine} \leftrightarrow \text{Final product} \]
**Part c.**
Reaction Scheme:
\[ \text{Reaction 1:} \quad \text{Benzene ring with methoxy group} + \text{Alkyl halide containing Br} \leftrightarrow \text{Final product} \]
**Question 5:**
*Draw the starting materials you could use to synthesize the following organic molecules, using only the Heck reaction for C-C bond-forming reactions.*
**Part a.**
Reaction Scheme:
\[ \text{Starting materials:} \quad \text{Alkene with halide group and H} + \text{Benzonitrile derivative} \leftrightarrow \text{Final product (benzene ring with cyano group and alkene chain)} \]
**Part b.**
Reaction Scheme:
\[ \text{Starting materials:} \quad \text{Alkene with halide group and H} + \text{Ethyl ester derivative} \leftrightarrow \text{Final product (benzene ring with ester group and alkene chain)} \]
Each part involves the selection of appropriate starting materials that adhere to the Suzuki and Heck reaction mechanisms for carbon-carbon bond formation.
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