hypothalamus thyrotropin-releasing hormone (TRH) inhibition inhibition anterior pituitary thyroid-stimulating hormone (TSH) thyroid gland thyroxine

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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The diagram below illustrates feedback control as exerted by the hormone thyroxine.
Following surgical removal of the thyroid gland, the level of TSH in the blood will increase.
inhibition
Thyroxine feedback loop
A
B
Which of the following best explains this increase?
с
hypothalamus
thyrotropin-releasing hormone (TRH)
D
anterior pituitary
thyroid-stimulating hormone (TSH)
inhibition
thyroid gland
thyroxine
Residual blood thyroxine, prior to thyroid gland removal, will bind to cells in the anterior
pituitary, signaling more TSH secretion.
Thyroxine that was stored in the anterior pituitary prior to thyroid gland removal will sig.
nal more TSH secretion.
Thyroxine will remain bound to thyroxine receptors on various body cells, and these
body cells will secrete additional hormones that stimulate the anterior pituitary to se
crete TSH.
A decrease in thyroxine levels means a loss of inhibition to the hypothalamus and ante
rior pituitary, leading to increased TSH secretion.
Transcribed Image Text:The diagram below illustrates feedback control as exerted by the hormone thyroxine. Following surgical removal of the thyroid gland, the level of TSH in the blood will increase. inhibition Thyroxine feedback loop A B Which of the following best explains this increase? с hypothalamus thyrotropin-releasing hormone (TRH) D anterior pituitary thyroid-stimulating hormone (TSH) inhibition thyroid gland thyroxine Residual blood thyroxine, prior to thyroid gland removal, will bind to cells in the anterior pituitary, signaling more TSH secretion. Thyroxine that was stored in the anterior pituitary prior to thyroid gland removal will sig. nal more TSH secretion. Thyroxine will remain bound to thyroxine receptors on various body cells, and these body cells will secrete additional hormones that stimulate the anterior pituitary to se crete TSH. A decrease in thyroxine levels means a loss of inhibition to the hypothalamus and ante rior pituitary, leading to increased TSH secretion.
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