Hypertension: The pathogenesis of essential hypertension is multifactorial and highly complex. Factors that play an important role in the pathogenesis of hypertension include genetics, activation of neurohormonal systems such as the sympathetic nervous system and renin-angiotensin-aldosterone system, abnormalities of resistance vessels, obesity, and increased dietary salt intake. Drugs used to treat hypertension target pathways and receptors linked to many of these pathogenic factors. Four classes of antihypertensive drugs were discussed in lecture. (1) Name these four classes. (2) name a drug in
4. Hypertension: The pathogenesis of essential hypertension is multifactorial and highly complex. Factors
that play an important role in the pathogenesis of hypertension include genetics, activation of
neurohormonal systems such as the sympathetic nervous system and renin-angiotensin-aldosterone
system, abnormalities of resistance vessels, obesity, and increased dietary salt intake. Drugs used to treat
hypertension target pathways and receptors linked to many of these pathogenic factors. Four classes of
antihypertensive drugs were discussed in lecture. (1) Name these four classes. (2) name a drug in
each class (3) describe that drug’s mechanism of action.
(answer in details and citation)
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