How much free energy will be released during ATP hydrolysis of ATP in this condition? Please write the formula you will be using to calculate.

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
Section: Chapter Questions
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Suppose the physiological concentrations of ATP, ADP and Pi are as follows in human liver cells.
ATP = 3.0 mM
ADP = 1.5 mM
PO4- = 2.0 mM
AG" for ATP hydrolysis is -30.5 kJoules/mole
R = 0.008314kJ/K/mol
T= 298K
How much free energy will be released during ATP hydrolysis of ATP in this condition? Please write the formula you will be using to calculate.
Transcribed Image Text:Suppose the physiological concentrations of ATP, ADP and Pi are as follows in human liver cells. ATP = 3.0 mM ADP = 1.5 mM PO4- = 2.0 mM AG" for ATP hydrolysis is -30.5 kJoules/mole R = 0.008314kJ/K/mol T= 298K How much free energy will be released during ATP hydrolysis of ATP in this condition? Please write the formula you will be using to calculate.
Expert Solution
Step 1

The following equation relate standard-state free energy of a reaction with the free energy:

G =G0'+RTlnQ

where, G = free energy

          G0' = standard-state free energy

                R = gas constant

                 T = temperature

                ln Q is the natural log of the reaction quotient

Q can be calculated as:

Q = [products][reactants]

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