How many stereoisomers are possible for ephedrine? Clearly show how you arrived at your determination. a. b. The stereoisomer shown below is the one that is pharmacologically active. What is the configuration of each of the asymmetric centers? Clearly label and state. OH NHCH3 CH3

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11. For many centuries, the Chinese have used extracts from a group erbs known as epedra to
treat asthma. A compound named ephedrine that has been isolated from these herbs was
found to be a potent dilator of air passages in the lungs. The structure for ephedrine is shown
below.
How many stereoisomers are possible for ephedrine? Clearly show how you arrived at
your determination.
a.
b. The stereoisomer shown below is the one that is pharmacologically active. What is the
configuration of each of the asymmetric centers? Clearly label and state.
HO
NHCH3
CH3
Transcribed Image Text:11. For many centuries, the Chinese have used extracts from a group erbs known as epedra to treat asthma. A compound named ephedrine that has been isolated from these herbs was found to be a potent dilator of air passages in the lungs. The structure for ephedrine is shown below. How many stereoisomers are possible for ephedrine? Clearly show how you arrived at your determination. a. b. The stereoisomer shown below is the one that is pharmacologically active. What is the configuration of each of the asymmetric centers? Clearly label and state. HO NHCH3 CH3
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We can determine the possible stereoisomers by deciding the number of chiral carbon centres present in given pharmaceutical moiety and arrangements of substitutions provides detailed idea about configuration. 

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