How many stereoisomers are possible for ephedrine? Clearly show how you arrived at your determination. a. b. The stereoisomer shown below is the one that is pharmacologically active. What is the configuration of each of the asymmetric centers? Clearly label and state. OH NHCH3 CH3
How many stereoisomers are possible for ephedrine? Clearly show how you arrived at your determination. a. b. The stereoisomer shown below is the one that is pharmacologically active. What is the configuration of each of the asymmetric centers? Clearly label and state. OH NHCH3 CH3
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Transcribed Image Text:11. For many centuries, the Chinese have used extracts from a group erbs known as epedra to
treat asthma. A compound named ephedrine that has been isolated from these herbs was
found to be a potent dilator of air passages in the lungs. The structure for ephedrine is shown
below.
How many stereoisomers are possible for ephedrine? Clearly show how you arrived at
your determination.
a.
b. The stereoisomer shown below is the one that is pharmacologically active. What is the
configuration of each of the asymmetric centers? Clearly label and state.
HO
NHCH3
CH3
Expert Solution

Step 1
We can determine the possible stereoisomers by deciding the number of chiral carbon centres present in given pharmaceutical moiety and arrangements of substitutions provides detailed idea about configuration.
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