How does the promoter region change from a DNase resistant site to a DNase hypersensitive site?

Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
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How does the promoter region change from a DNase resistant site to a DNase hypersensitive site?

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DNase I hypersensitive sites (DHSs) are sites on chromatin which are sensitive to cleavage by the DNase enzyme. In this site of DHSs chromatin lose its condensed structure due to which DNA becomes accessible and degraded by DNase 1.

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