How can human females and males function normally, despite carrying different umbers of the X chromosome? Females compensate for their double genetic dose of X chromosome, by tightly condensing one X chromosome in each cell into a Barr body, making it inactive

Biochemistry
9th Edition
ISBN:9781319114671
Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.
Chapter1: Biochemistry: An Evolving Science
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How can human females and males function normally, despite carrying different
numbers of the X chromosome?
Females compensate for their double genetic dose of X chromosome, by tightly
condensing one X chromosome in each cell into a Barr body, making it inactive.
Females must always be heterozygous for genes located in the X chromosome.
Males compensate for their single genetic dose of X chromosome by doubling
the expression of the alleles present on their only X.
Males must always be heterozygous for genes located in the X chromosome.
Transcribed Image Text:How can human females and males function normally, despite carrying different numbers of the X chromosome? Females compensate for their double genetic dose of X chromosome, by tightly condensing one X chromosome in each cell into a Barr body, making it inactive. Females must always be heterozygous for genes located in the X chromosome. Males compensate for their single genetic dose of X chromosome by doubling the expression of the alleles present on their only X. Males must always be heterozygous for genes located in the X chromosome.
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