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Chemistry
HO NHz لم

HO NHz لم

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Predict the major product of the following reaction.

### Reaction Mechanism Overview **Reactants:** - **Structure on the Left:** This is a chemical structure featuring a benzene ring with a hydroxyl group (OH) and an amine group (NH₂) attached to it. This compound is known as 4-aminophenol. - **Structure in the Middle:** This represents an acid anhydride, characterized by a central carbonyl group bonded to two acyl groups. This specific anhydride is acetic anhydride, with each acyl group being a methyl group attached to the carbonyl carbon. **Reaction Arrow:** - The arrow indicates the direction of the chemical reaction, pointing from the reactants to the expected product(s), which are not shown in the image. ### Reaction Description In this reaction, 4-aminophenol is reacting with acetic anhydride. This type of reaction is typically an acylation reaction, where the hydroxyl and amine groups can undergo acetylation. The most likely products would be an acylated amine and possibly an acylated hydroxyl group, depending on reaction conditions and stoichiometry. ### Educational Focus This example could be used to illustrate: - The concept of acylation reactions in organic chemistry. - The reactivity of amines and phenols with acid anhydrides. - Mechanistic steps in acetylation processes. - The impact of functional group proximity on reactivity and product formation. This visual setup helps students understand how functional groups participate in typical reactions involving derivatization like acetylation, a key reaction in synthesis and pharmaceutical chemistry.
Transcribed Image Text:### Reaction Mechanism Overview **Reactants:** - **Structure on the Left:** This is a chemical structure featuring a benzene ring with a hydroxyl group (OH) and an amine group (NH₂) attached to it. This compound is known as 4-aminophenol. - **Structure in the Middle:** This represents an acid anhydride, characterized by a central carbonyl group bonded to two acyl groups. This specific anhydride is acetic anhydride, with each acyl group being a methyl group attached to the carbonyl carbon. **Reaction Arrow:** - The arrow indicates the direction of the chemical reaction, pointing from the reactants to the expected product(s), which are not shown in the image. ### Reaction Description In this reaction, 4-aminophenol is reacting with acetic anhydride. This type of reaction is typically an acylation reaction, where the hydroxyl and amine groups can undergo acetylation. The most likely products would be an acylated amine and possibly an acylated hydroxyl group, depending on reaction conditions and stoichiometry. ### Educational Focus This example could be used to illustrate: - The concept of acylation reactions in organic chemistry. - The reactivity of amines and phenols with acid anhydrides. - Mechanistic steps in acetylation processes. - The impact of functional group proximity on reactivity and product formation. This visual setup helps students understand how functional groups participate in typical reactions involving derivatization like acetylation, a key reaction in synthesis and pharmaceutical chemistry.
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