Hemoglobin (Hb) can react with both O2 and CO at 37 °C.  The reaction below shows how CO can displace O2 from hemoglobin with a K = 2.0 x 102 : HbO2(aq) + CO(g)  <===>  HbCO(aq) + O2(g) If the ratio [HbCO]/[HbO2] comes close to 1, death will happen.  What partial pressure of CO is fatal?  Assume the partial pressure of O2 is 0.20 atm (since air is 20% O2). 4×10−4atm 1×10−3atm 200 atm 1000 atm 0.2 atm

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Hemoglobin (Hb) can react with both O2 and CO at 37 °C.  The reaction below shows how CO can displace O2 from hemoglobin with a K = 2.0 x 10:

HbO2(aq) + CO(g)  <===>  HbCO(aq) + O2(g)

If the ratio [HbCO]/[HbO2] comes close to 1, death will happen.  What partial pressure of CO is fatal?  Assume the partial pressure of O2 is 0.20 atm (since air is 20% O2).

4×10−4atm
1×10−3atm
200 atm
1000 atm
0.2 atm
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