Hemiacetals are a useful functional group in synthetic chemistry, and although their straight- chain forms are not often found in drug structures, cyclic forms are relatively common. The molecule 5-hydroxyhexanal (1) is an example of a molecule whose straight-chain form is in equilibrium with a 6-membered cyclic form (2). H* LHOT 1 OH

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Chapter1: Chemical Foundations
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Provide a complete electronic mechanism for the conversion of 1 into 2. Ensure all proton transfer steps are explicitly in the mechanism.

6.
Answer ALL parts of this question.
Hemiacetals are a useful functional group in synthetic chemistry, and although their straight-
chain forms are not often found in drug structures, cyclic forms are relatively common. The
molecule 5-hydroxyhexanal (1) is an example of a molecule whose straight-chain form is in
equilibrium with a 6-membered cyclic form (2).
Lo
LHOT
H*
OH
1.
Transcribed Image Text:6. Answer ALL parts of this question. Hemiacetals are a useful functional group in synthetic chemistry, and although their straight- chain forms are not often found in drug structures, cyclic forms are relatively common. The molecule 5-hydroxyhexanal (1) is an example of a molecule whose straight-chain form is in equilibrium with a 6-membered cyclic form (2). Lo LHOT H* OH 1.
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