Heart 1 Frog heart 1 Time (s) Dr Loewi had continued measuring for longer after stimulation, which of the following would have ccurred? O The heart rate would remain low O The heart rate would gradually return to the pre-stimulation level Contraction force

Human Anatomy & Physiology (11th Edition)
11th Edition
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Author:Elaine N. Marieb, Katja N. Hoehn
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Chapter1: The Human Body: An Orientation
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Otto Loewi and the proof of electrochemical transmission.
In early physiology there was a lot of discussion as to whether nervous transmission was electrical or
chemical or both. Otto Loewi conducted the definitive experiment that showed electrochemical
transmission using frog hearts and the vagus nerve. Loewi knew that vagus nerve stimulation lowered
heart rate as shown below. So, he isolated a frog heart with its attached nerve, and measured the heart
rate before and after stimulating the vagus nerve with an electrical impulse.
Vagus
Stimulate
Stimulate vagus
nerve of heart 1
nerve
Heart 1
Frog
heart 1
Time (s)
If Dr Loewi had continued measuring for longer after stimulation, which of the following would have
occurred?
O The heart rate would remain low
O The heart rate would gradually return to the pre-stimulation level
O The heart rate would fluctuate between high and low
O The contraction force would remain low as the heart rate rose
O None of the above
Contraction force
Transcribed Image Text:Otto Loewi and the proof of electrochemical transmission. In early physiology there was a lot of discussion as to whether nervous transmission was electrical or chemical or both. Otto Loewi conducted the definitive experiment that showed electrochemical transmission using frog hearts and the vagus nerve. Loewi knew that vagus nerve stimulation lowered heart rate as shown below. So, he isolated a frog heart with its attached nerve, and measured the heart rate before and after stimulating the vagus nerve with an electrical impulse. Vagus Stimulate Stimulate vagus nerve of heart 1 nerve Heart 1 Frog heart 1 Time (s) If Dr Loewi had continued measuring for longer after stimulation, which of the following would have occurred? O The heart rate would remain low O The heart rate would gradually return to the pre-stimulation level O The heart rate would fluctuate between high and low O The contraction force would remain low as the heart rate rose O None of the above Contraction force
What happened to the heart rate of the second heart?
O It accelerated
O It slowed down to a rate that was less than that of the stimulated heart
O It slowed down to a rate that was more than that of the stimulated heart
O It slowed down to a rate that was the same as that of the stimulated heart
O It didn't change rate
Transcribed Image Text:What happened to the heart rate of the second heart? O It accelerated O It slowed down to a rate that was less than that of the stimulated heart O It slowed down to a rate that was more than that of the stimulated heart O It slowed down to a rate that was the same as that of the stimulated heart O It didn't change rate
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