he vertical transmission of certain communicable diseases from mother-to-child during pregnancy and birth is of great concern to public health practitioners because it represents a critical period for intervention. If practitioners can determine at birth whether the disease has been transmitted from mother-to-child, they can act immediately to provide the child with treatment. Syphilis is a disease with high risk for vertical transmission from mother-to-child. If a child becomes infected and is not treated, there can be negative health outcome such as blindness, deafness, and neurological damage. Inspired by the advent of rapid HIV tests that provide quick results and are minimally invasive, suppose that researchers have been working to develop a similar test that can be used for syphilis. After obtaining appropriate institutional approval and patient consent, the researchers test their rapid syphilis test at several birthing hospitals and compare it to the gold standard laboratory test. A total of 77 samples are collected from infants at the time of birth. The gold standard identifies that 45 of the 77 tests were negative but the rapid test show 63 negative results. Of these 63 negative rapid test results, 43 are confirmed to be true negatives. Question: Using the above information, calculate the positive predictive value (PPV). Round to the nearest whole number. Express all of your answers as a percent (%) PPV = TP / (TP + FP):
The vertical transmission of certain communicable diseases from mother-to-child during pregnancy and birth is of great concern to public health practitioners because it represents a critical period for intervention. If practitioners can determine at birth whether the disease has been transmitted from mother-to-child, they can act immediately to provide the child with treatment.
Syphilis is a disease with high risk for vertical transmission from mother-to-child. If a child becomes infected and is not treated, there can be negative health outcome such as blindness, deafness, and neurological damage. Inspired by the advent of rapid HIV tests that provide quick results and are minimally invasive, suppose that researchers have been working to develop a similar test that can be used for syphilis. After obtaining appropriate institutional approval and patient consent, the researchers test their rapid syphilis test at several birthing hospitals and compare it to the gold standard laboratory test.
A total of 77 samples are collected from infants at the time of birth. The gold standard identifies that 45 of the 77 tests were negative but the rapid test show 63 negative results. Of these 63 negative rapid test results, 43 are confirmed to be true negatives.
Question:
Using the above information, calculate the positive predictive value (PPV). Round to the nearest whole number. Express all of your answers as a percent (%)
PPV = TP / (TP + FP):
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