H3PO4 HO. + H3C CH3 H3C HO. он HO. acetic acid acetic anhydride (C,H¸O,) (C,H_0,) salicylic acid (C,H_O,) 102 g/ mol CH3 acetylsalicylic acid (CHO) 138 g/mol d= 1.08 g/mL 180 g/mol Reaction for synthesis of acetylsalicylic acid

Fundamentals Of Analytical Chemistry
9th Edition
ISBN:9781285640686
Author:Skoog
Publisher:Skoog
Chapter16: Applications Of Neutralization Titrations
Section: Chapter Questions
Problem 16.9QAP
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Provide in detail, the aspirin synthesis mechanism. 

H3PO.
HO.
HO.
+ H3C
H3C
CH3
HO
HO.
acetic acid
acetic anhydride
(C,H,0,)
(C,H,0,)
salicylic acid
(C,H,0,)
102 g/ mol
CH3
acetylsalicylic acid
(CH,0)
138 g/mol
d = 1.08 g/ml
180 g/mol
Reaction for synthesis of acetylsalicylic acid
O=
O=U
Transcribed Image Text:H3PO. HO. HO. + H3C H3C CH3 HO HO. acetic acid acetic anhydride (C,H,0,) (C,H,0,) salicylic acid (C,H,0,) 102 g/ mol CH3 acetylsalicylic acid (CH,0) 138 g/mol d = 1.08 g/ml 180 g/mol Reaction for synthesis of acetylsalicylic acid O= O=U
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