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H3C NH₂ H3C Amides can be hydrolyzed to yield carboxylic acids. The conditions are much more severe than those for other carboxylic acid derivatives. Acidic hydrolysis occurs by addition of water to the protonated carbonyl, followed by proton transfer to make the nitrogen a better leaving group. The reactions are reversible, and the reaction is driven to completion by protonation of NH3 at the end. 20 H3C- Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instructions H3O* XT -OH NH3 + OH H₂O: NH3 H3C :0: OH NH3 H3O+

H3C NH₂ H3C Amides can be hydrolyzed to yield carboxylic acids. The conditions are much more severe than those for other carboxylic acid derivatives. Acidic hydrolysis occurs by addition of water to the protonated carbonyl, followed by proton transfer to make the nitrogen a better leaving group. The reactions are reversible, and the reaction is driven to completion by protonation of NH3 at the end. 20 H3C- Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instructions H3O* XT -OH NH3 + OH H₂O: NH3 H3C :0: OH NH3 H3O+

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
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Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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H3C H3C H3C OH Amides can be hydrolyzed to yield carboxylic acids. The conditions are much more severe than those for other carboxylic acid derivatives. Acidic hydrolysis occurs by addition of water to the protonated carbonyl, followed by proton transfer to make the nitrogen a better leaving group. The reactions are reversible, and the reaction is driven to completion by protonation of NH3 at the end. Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instructions NOC XT .H + NH3 NH₂ -OH H3O+ H₂O: NH3 H3C :0: OH NH3 H3O+
Transcribed Image Text:H3C H3C H3C OH Amides can be hydrolyzed to yield carboxylic acids. The conditions are much more severe than those for other carboxylic acid derivatives. Acidic hydrolysis occurs by addition of water to the protonated carbonyl, followed by proton transfer to make the nitrogen a better leaving group. The reactions are reversible, and the reaction is driven to completion by protonation of NH3 at the end. Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instructions NOC XT .H + NH3 NH₂ -OH H3O+ H₂O: NH3 H3C :0: OH NH3 H3O+
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