H11.37 - Level 3 Unanswered • 3 attempts left What is the final, major product of this reaction? A a B b с с D d CH3 OMe 1) H3PO4 2) NaN3, acetone / H20 (50:50) он Br a) OMe b) OMe N3 c) OMe b) OMe N3 N3
H11.37 - Level 3 Unanswered • 3 attempts left What is the final, major product of this reaction? A a B b с с D d CH3 OMe 1) H3PO4 2) NaN3, acetone / H20 (50:50) он Br a) OMe b) OMe N3 c) OMe b) OMe N3 N3
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
Question
![**Reaction Identification and Analysis**
**Question: What is the final, major product of this reaction?**
**Options:**
1. **A**: a
2. **B**: b
3. **C**: c
4. **D**: d
**Reaction Scheme:**
The given reaction starts with a specific substrate and undergoes a two-step transformation:
1. **Step 1**: The substrate reacts with H₃PO₄ (phosphoric acid).
2. **Step 2**: The product from Step 1 is then treated with NaN₃ (sodium azide) in a 50:50 mixture of acetone and water.
The reaction sequence can be represented as:
\[ \text{CH}_3\text{(CH}_2\text{)}_2\text{OH}\overset{\text{H}_3\text{PO}_4}{\rightarrow}\text{intermediate}\overset{\text{NaN}_3}{\rightarrow}\text{final product} \]
**Possible Products:**
The image below shows the set of possible products labeled as:
- **A**: a
- **B**: b
- **C**: c
- **D**: d
Each option is visually represented by a different molecular structure featuring variations according to the positioning and orientation of substituents like OMe (methoxy group) and N₃ (azido group).
**Diagrams:**
The molecular structures for the potential products (a, b, c, d) are provided:
a) Features an azide (-N₃) group at a specific position with a particular stereochemistry.
b) Shows a different positioning and orientation of the azide group compared to 'a'.
c) Another distinct structure with the azide group and methoxy group in different orientations and positions.
d) Yet another unique arrangement of the functional groups, distinct from options a, b, and c.
**Discussion:**
To identify the final product, one must consider:
1. The initial functional groups and their reactivity.
2. The effect of H₃PO₄ and NaN₃ on the substrate.
3. The probable intermediates in each step.
4. The final outcome based on stereochemistry and regiochemistry principles.
**Conclusion:**
Evaluate each possible product (a, b, c, d) based on your knowledge of organic](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2F7230fc23-0539-4535-bb9f-ac414a441eeb%2Fae569033-cce2-45c4-9755-be4fb8635b4c%2Fyxe3r5_processed.jpeg&w=3840&q=75)
Transcribed Image Text:**Reaction Identification and Analysis**
**Question: What is the final, major product of this reaction?**
**Options:**
1. **A**: a
2. **B**: b
3. **C**: c
4. **D**: d
**Reaction Scheme:**
The given reaction starts with a specific substrate and undergoes a two-step transformation:
1. **Step 1**: The substrate reacts with H₃PO₄ (phosphoric acid).
2. **Step 2**: The product from Step 1 is then treated with NaN₃ (sodium azide) in a 50:50 mixture of acetone and water.
The reaction sequence can be represented as:
\[ \text{CH}_3\text{(CH}_2\text{)}_2\text{OH}\overset{\text{H}_3\text{PO}_4}{\rightarrow}\text{intermediate}\overset{\text{NaN}_3}{\rightarrow}\text{final product} \]
**Possible Products:**
The image below shows the set of possible products labeled as:
- **A**: a
- **B**: b
- **C**: c
- **D**: d
Each option is visually represented by a different molecular structure featuring variations according to the positioning and orientation of substituents like OMe (methoxy group) and N₃ (azido group).
**Diagrams:**
The molecular structures for the potential products (a, b, c, d) are provided:
a) Features an azide (-N₃) group at a specific position with a particular stereochemistry.
b) Shows a different positioning and orientation of the azide group compared to 'a'.
c) Another distinct structure with the azide group and methoxy group in different orientations and positions.
d) Yet another unique arrangement of the functional groups, distinct from options a, b, and c.
**Discussion:**
To identify the final product, one must consider:
1. The initial functional groups and their reactivity.
2. The effect of H₃PO₄ and NaN₃ on the substrate.
3. The probable intermediates in each step.
4. The final outcome based on stereochemistry and regiochemistry principles.
**Conclusion:**
Evaluate each possible product (a, b, c, d) based on your knowledge of organic
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