Organic Chemistry
8th Edition
ISBN:9781305580350
Author:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Chapter18: Functional Derivatives Of Carboxylic Acids
Section: Chapter Questions
Problem 18.69P
Related questions
Concept explainers
Question
What is the major product of these reactions? Could you explain how you got the products?
![### Image Transcription for Educational Website
#### Chemical Reactions
**d)** A chemical reaction involving:
- A ketone compound:
- ![attach molecule image] with a formula containing a ketone group.
- Mixed with a diethyl phosphorochloridate compound:
- ![attach molecule image] a triphosphate ester.
- This reaction proceeds using:
- **NaOH/H₂O & heptane** as the medium.
- **Aliquat 336** as the phase-transfer catalyst.
---
**e)** A multi-step reaction involving:
1. Starting with an alkyl halide:
- ![attach molecule image] with a chlorine atom.
2. Reacted with **Mg in ether** to form a Grignard reagent.
3. Sequential reaction:
- **H** indicates acid-workup with an aromatic ketone.
- [second structure] **H⁺/H₂O** for aqueous acidic workup.
---
**f)** A two-step reaction involving:
1. Starting with an amide compound:
- ![attach molecule image] with a methyl and an aromatic group.
2. Reactions proceed with:
- **H₂O, H₂SO₄, Δ** indicating hydrolysis under acidic and heat conditions.
3. Finally treated with:
- **NH₄OH** for neutralization or a modification step.
---
These chemical processes illustrate important methods in organic synthesis, including Grignard reaction formation and hydrolysis under acidic conditions, useful in constructing complex organic molecules.](/v2/_next/image?url=https%3A%2F%2Fcontent.bartleby.com%2Fqna-images%2Fquestion%2Fb442e5ac-22ff-4c91-9e07-cc3b96de7980%2Fbf5309f6-1aed-4dcb-8085-d788efdf418e%2Fn5xng9_processed.jpeg&w=3840&q=75)
Transcribed Image Text:### Image Transcription for Educational Website
#### Chemical Reactions
**d)** A chemical reaction involving:
- A ketone compound:
- ![attach molecule image] with a formula containing a ketone group.
- Mixed with a diethyl phosphorochloridate compound:
- ![attach molecule image] a triphosphate ester.
- This reaction proceeds using:
- **NaOH/H₂O & heptane** as the medium.
- **Aliquat 336** as the phase-transfer catalyst.
---
**e)** A multi-step reaction involving:
1. Starting with an alkyl halide:
- ![attach molecule image] with a chlorine atom.
2. Reacted with **Mg in ether** to form a Grignard reagent.
3. Sequential reaction:
- **H** indicates acid-workup with an aromatic ketone.
- [second structure] **H⁺/H₂O** for aqueous acidic workup.
---
**f)** A two-step reaction involving:
1. Starting with an amide compound:
- ![attach molecule image] with a methyl and an aromatic group.
2. Reactions proceed with:
- **H₂O, H₂SO₄, Δ** indicating hydrolysis under acidic and heat conditions.
3. Finally treated with:
- **NH₄OH** for neutralization or a modification step.
---
These chemical processes illustrate important methods in organic synthesis, including Grignard reaction formation and hydrolysis under acidic conditions, useful in constructing complex organic molecules.
Expert Solution

This question has been solved!
Explore an expertly crafted, step-by-step solution for a thorough understanding of key concepts.
This is a popular solution!
Trending now
This is a popular solution!
Step by step
Solved in 2 steps with 1 images

Knowledge Booster
Learn more about
Need a deep-dive on the concept behind this application? Look no further. Learn more about this topic, chemistry and related others by exploring similar questions and additional content below.Recommended textbooks for you

Organic Chemistry
Chemistry
ISBN:
9781305580350
Author:
William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:
Cengage Learning

Chemistry for Today: General, Organic, and Bioche…
Chemistry
ISBN:
9781305960060
Author:
Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:
Cengage Learning

Organic Chemistry
Chemistry
ISBN:
9781305580350
Author:
William H. Brown, Brent L. Iverson, Eric Anslyn, Christopher S. Foote
Publisher:
Cengage Learning

Chemistry for Today: General, Organic, and Bioche…
Chemistry
ISBN:
9781305960060
Author:
Spencer L. Seager, Michael R. Slabaugh, Maren S. Hansen
Publisher:
Cengage Learning