H ept: HIN O Penicillin V (anti-infective) A H -N- S H-O B H CF3 CF3 LO H N. Z-H Flecainide (cardiovascular drug) C H-Br F-H H-1 CI-H

Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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How do you know how to find the most acidic hydrogens in these problems? 

Question 3: Circle the most acidic of the hydrogen atoms highlighted in bold
(Concept: Acids/Bases).
H
E
Penicillin V
(anti-infective)
HIN
O
F3C-P-O
H
A
Z
S
H-O
F
H
B
CF3
H CF 3
OH
P-O
N
O
Flecainide
(cardiovascular drug)
H
F
Z-H
H
H
0=5=0
C
H-Br
F-H
H-
CI-H
H
G
F
F
D
1
H₂N
די
N
0
1
CI
T
NH, O NH
Amiloride
(cardiovascular drug)
O-I
Z
H
Н
HIN
O
IZ
H
H
a-
H
Transcribed Image Text:Question 3: Circle the most acidic of the hydrogen atoms highlighted in bold (Concept: Acids/Bases). H E Penicillin V (anti-infective) HIN O F3C-P-O H A Z S H-O F H B CF3 H CF 3 OH P-O N O Flecainide (cardiovascular drug) H F Z-H H H 0=5=0 C H-Br F-H H- CI-H H G F F D 1 H₂N די N 0 1 CI T NH, O NH Amiloride (cardiovascular drug) O-I Z H Н HIN O IZ H H a- H
Expert Solution
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Note: According to our guidelines we are supposed to answer only first three subpart. Kindly repost other part in next question 

Hydrogen attached to acidic group is most acidic because in this Hydrogen is attached to the most electronegative atom is most acidic .

Hydrogen attached to the basic group is less acidic.

 

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