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H C0 H₂CO CEN NaOH, H.O LiAIH, THF H30* PhMgBr H;o - F D E

H C0 H₂CO CEN NaOH, H.O LiAIH, THF H30* PhMgBr H;o - F D E

Chemistry
Chemistry
10th Edition
ISBN:9781305957404
Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste
Chapter1: Chemical Foundations
Section: Chapter Questions
Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...
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Write the structure of the products of the following reaction

The image depicts a chemical structure and a reaction scheme involving a compound derived from an aromatic ring with methoxy groups and a cyano group (C≡N). **Chemical Structure:** - The central structure is a benzene ring with two methoxy groups (CH₃O) attached to adjacent carbon atoms. **Reactions Overview:** 1. **Conversion to Compound D:** - Reagents: NaOH, H₂O - This pathway involves a basic hydrolysis reaction. 2. **Conversion to Compound E:** - Reagents: LiAlH₄, THF followed by H₃O⁺ - This pathway involves reduction followed by acidic workup. 3. **Conversion to Compound F:** - Reagents: PhMgBr followed by H₃O⁺ - This pathway involves Grignard reaction followed by acidic workup. **Explanation of Steps:** - **Pathway D:** Treatment with sodium hydroxide and water suggests a nucleophilic substitution or elimination reaction, leading to the formation of compound D. - **Pathway E:** The use of lithium aluminum hydride (LiAlH₄) indicates a reduction process, typically reducing the nitrile group to a primary amine or similar reduction products, forming compound E. - **Pathway F:** The reaction with phenylmagnesium bromide (PhMgBr) and subsequent hydrolysis suggests a Grignard reaction, likely forming a new carbon-carbon bond, resulting in compound F.
Transcribed Image Text:The image depicts a chemical structure and a reaction scheme involving a compound derived from an aromatic ring with methoxy groups and a cyano group (C≡N). **Chemical Structure:** - The central structure is a benzene ring with two methoxy groups (CH₃O) attached to adjacent carbon atoms. **Reactions Overview:** 1. **Conversion to Compound D:** - Reagents: NaOH, H₂O - This pathway involves a basic hydrolysis reaction. 2. **Conversion to Compound E:** - Reagents: LiAlH₄, THF followed by H₃O⁺ - This pathway involves reduction followed by acidic workup. 3. **Conversion to Compound F:** - Reagents: PhMgBr followed by H₃O⁺ - This pathway involves Grignard reaction followed by acidic workup. **Explanation of Steps:** - **Pathway D:** Treatment with sodium hydroxide and water suggests a nucleophilic substitution or elimination reaction, leading to the formation of compound D. - **Pathway E:** The use of lithium aluminum hydride (LiAlH₄) indicates a reduction process, typically reducing the nitrile group to a primary amine or similar reduction products, forming compound E. - **Pathway F:** The reaction with phenylmagnesium bromide (PhMgBr) and subsequent hydrolysis suggests a Grignard reaction, likely forming a new carbon-carbon bond, resulting in compound F.
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