Given the structures of cocaine (right) and its free base (left) below: a. Would you expect K for the cocaine to be greater or less than 1.0?  Explain. b. Would K for the free base be higher or lower than for cocaine?  Explain. c. To favor the equilibrium towards the free base, would you make the aqueous solution acidic or basic?  Explain. (Hint: think of Le Chatelier’s principle).

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Given the structures of cocaine (right) and its free base (left) below:

a. Would you expect K for the cocaine to be greater or less than 1.0?  Explain.

b. Would K for the free base be higher or lower than for cocaine?  Explain.

c. To favor the equilibrium towards the free base, would you make the aqueous solution acidic or basic?  Explain. (Hint: think of Le Chatelier’s principle).

CH,
CH,
H3C-N.
H;C-N
+ H*
+
Transcribed Image Text:CH, CH, H3C-N. H;C-N + H* +
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