Give all questions answers with explanation please 7. The following carboxylic acid derivatives are used for de novo synthesis of the amidesfound in peptides. The pKa values of the protonated leaving groups are shown.NO2N=NHOHO-N.HOHSpka = 7.1pka = 6.0pka = 10.0pka = 4.3%3DNO2N=NPNPOsu2-SHPYHOBIa. Rank the derivatives from most reactive (1) to least reactive (4) (under the structuresabove, or using the abbreviations) as carboxylic acid derivatives. Explain yourreasoning briefly.b. What carboxylic acid derivative is more reactive than all of these derivatives? Explainyour answer.

Solution- (a). Ranking derivateves from most reactive to least reactive as caroxcylic acid is…

Answered: Give all questions answers with…

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Chemistry

Give all questions answers with explanation please

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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Concept explainers

Aldehydes and Ketones

Aldehydes and ketones are organic compounds that have a carbonyl group, C = O, as their functional group. They both differ in the placement of this carbonyl group in their structures.

Question

Give all questions answers with explanation please

7. The following carboxylic acid derivatives are used for de novo synthesis of the amides
found in peptides. The pKa values of the protonated leaving groups are shown.
NO2
N=N
HO
HO-N.
HO
HS
pka = 7.1
pka = 6.0
pka = 10.0
pka = 4.3
%3D
NO2
N=N
PNP
Osu
2-SHPY
HOBI
a. Rank the derivatives from most reactive (1) to least reactive (4) (under the structures
above, or using the abbreviations) as carboxylic acid derivatives. Explain your
reasoning briefly.
b. What carboxylic acid derivative is more reactive than all of these derivatives? Explain
your answer.

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