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Genomic imprinting The human IGF2 gene is autosomal and maternally imprinted. You have found two alleles of this gene that encode two different forms of the IGF2 protein distinguishable by gel electrophoresis. One allele encodes a 60K (Kilodalton) blood protein; the other allele encodes a 50K blood protein. In an analysis of blood proteins from a couple named Bill and Joan, you find only the 60K protein in Joan's blood, and only the 50K protein in Bill's blood. You then look at their children: Jill is producing only the 50K protein, while Bill Jr. is producing only the 60K protein. 2 Draw a pedigree like the one below showing Bill Sr., Joan, and their two children. Leave enough room in the shapes to write what you know about the genotype of each person. Bill Sr. Joan Bill Jr. Jill Inside each square and circle indicate the genotype of that individual (e.g., 60/60; 60/50; or 50/50). Underline any silenced alleles; use a question mark to indicate an unknown allele (e.g., 60/?). Upload your pedigree as a picture. Make sure your pedigree is neat and easy to read. If we cannot read your pedigree, it will receive a zero grade. Likewise, make sure your picture is right-side-up. Pictures that are upside down or sideways will receive a zero grade. ↑ Drag n' Drop here or Browse

Genomic imprinting The human IGF2 gene is autosomal and maternally imprinted. You have found two alleles of this gene that encode two different forms of the IGF2 protein distinguishable by gel electrophoresis. One allele encodes a 60K (Kilodalton) blood protein; the other allele encodes a 50K blood protein. In an analysis of blood proteins from a couple named Bill and Joan, you find only the 60K protein in Joan's blood, and only the 50K protein in Bill's blood. You then look at their children: Jill is producing only the 50K protein, while Bill Jr. is producing only the 60K protein. 2 Draw a pedigree like the one below showing Bill Sr., Joan, and their two children. Leave enough room in the shapes to write what you know about the genotype of each person. Bill Sr. Joan Bill Jr. Jill Inside each square and circle indicate the genotype of that individual (e.g., 60/60; 60/50; or 50/50). Underline any silenced alleles; use a question mark to indicate an unknown allele (e.g., 60/?). Upload your pedigree as a picture. Make sure your pedigree is neat and easy to read. If we cannot read your pedigree, it will receive a zero grade. Likewise, make sure your picture is right-side-up. Pictures that are upside down or sideways will receive a zero grade. ↑ Drag n' Drop here or Browse

Human Anatomy & Physiology (11th Edition)
Human Anatomy & Physiology (11th Edition)
11th Edition
ISBN:9780134580999
Author:Elaine N. Marieb, Katja N. Hoehn
Publisher:Elaine N. Marieb, Katja N. Hoehn
Chapter1: The Human Body: An Orientation
Section: Chapter Questions
Problem 1RQ: The correct sequence of levels forming the structural hierarchy is A. (a) organ, organ system,...
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Genomic imprinting The human IGF2 gene is autosomal and maternally imprinted. You have found two alleles of this gene that encode two different forms of the IGF2 protein distinguishable by gel electrophoresis. One allele encodes a 60K (Kilodalton) blood protein; the other allele encodes a 50K blood protein. In an analysis of blood proteins from a couple named Bill and Joan, you find only the 60K protein in Joan's blood, and only the 50K protein in Bill's blood. You then look at their children: Jill is producing only the 50K protein, while Bill Jr. is producing only the 60K protein. 2 Draw a pedigree like the one below showing Bill Sr., Joan, and their two children. Leave enough room in the shapes to write what you know about the genotype of each person. Bill Sr. Joan Bill Jr. Jill Inside each square and circle indicate the genotype of that individual (e.g., 60/60; 60/50; or 50/50). Underline any silenced alleles; use a question mark to indicate an unknown allele (e.g., 60/?). Upload your pedigree as a picture. Make sure your pedigree is neat and easy to read. If we cannot read your pedigree, it will receive a zero grade. Likewise, make sure your picture is right-side-up. Pictures that are upside down or sideways will receive a zero grade. ↑ Drag n' Drop here or Browse
Transcribed Image Text:Genomic imprinting The human IGF2 gene is autosomal and maternally imprinted. You have found two alleles of this gene that encode two different forms of the IGF2 protein distinguishable by gel electrophoresis. One allele encodes a 60K (Kilodalton) blood protein; the other allele encodes a 50K blood protein. In an analysis of blood proteins from a couple named Bill and Joan, you find only the 60K protein in Joan's blood, and only the 50K protein in Bill's blood. You then look at their children: Jill is producing only the 50K protein, while Bill Jr. is producing only the 60K protein. 2 Draw a pedigree like the one below showing Bill Sr., Joan, and their two children. Leave enough room in the shapes to write what you know about the genotype of each person. Bill Sr. Joan Bill Jr. Jill Inside each square and circle indicate the genotype of that individual (e.g., 60/60; 60/50; or 50/50). Underline any silenced alleles; use a question mark to indicate an unknown allele (e.g., 60/?). Upload your pedigree as a picture. Make sure your pedigree is neat and easy to read. If we cannot read your pedigree, it will receive a zero grade. Likewise, make sure your picture is right-side-up. Pictures that are upside down or sideways will receive a zero grade. ↑ Drag n' Drop here or Browse
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