4. Gamma turns are divided into two classes based on the phi and psi rotationalbond angles of the residue at positions n + 1. In the classical gamma turn, theresidue at position n + 1 has phi = + 70 degrees and psi = -60 degrees, whereasin the inverse gamma turn, the residue at position n + 1 has phi = - 70 degreesand psi = + 60 degrees. Draw a Ramachandran plot and indicate the location ofthese bond angles on your plot.

An illustration of the permitted and forbidden areas of the phi and psi dihedral angles in the…

Answered: Gamma turns are divided into two…

Biochemistry

9th Edition

ISBN:9781319114671

Author:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Publisher:Lubert Stryer, Jeremy M. Berg, John L. Tymoczko, Gregory J. Gatto Jr.

Chapter1: Biochemistry: An Evolving Science

Section: Chapter Questions

Problem 1P

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Which of the following is an anomer of B-D-gulopyranose? O O го ОН H ОН H ОН H H ОН CH₂OH -II- H H ОН ОН CH2OH H ОН ОН CH2OH О 0. H CH2OH то Н H H ОН H H - о H ОН ОН H ОН H ОН ОН H О ОН ОН H N
Please Provide the name of the following nitrogen-containing heterocyclic base for both of the following
How do you draw the resolution to the double Holliday junction? Each step explained in detail.
The commercial sample of carboxyl esterase contained 15.0 mg of enxyme in 0.30 mL of suspension. In your experiment, you add 0.090 mL of this suspension to the sample tube that contains a total volume of 3.0 mL. How many mg of carboxyl esterase enzyme do you have in the sample tube?
2.7 Now that you have figured out the reaction mechanism, let's explore the action mechanism of the following drug. Notice that this molecule is composed of two chloroethylamine groups and therefore can react with two different nucleophiles. Complete the following reaction mechanism. R-N Cl CL + R'-NH₂ R"-NH₂ The above reaction is responsible for the activity of the drug. Because of its ability to react with two nucleophiles, the drug can create a bridge between two biologically active molecules and disrupt their activity. This process is known as 'cross-linking'. For example, it can react with two DNA strands and prevent their separation during replication. This will cause cytotoxicity and cell death. 2.8 Draw a scheme/cartoon to represent the general idea of chemical cross-linking described above.
Each group will be provided with 20 g double-stranded DNA oligomer in STE buffer (0.1M NaCl/ Tris/ 10 mM EDTA, pH 7.4). The sequence of one strand of the oligomer is: 5’-AATGGTACGTATACTTTAT-3’ - show a table of % denaturation of DNA at different temperatures, using the equation provided in “Calculation” - plot a graph of % denaturation of DNA vs different temperatures with clear label and title, and hence determine the experimental Tm of the DNA sample - calculate the theoretical Tm of the sample using Marmur and Doty equation, compare the experimental Tm with theoretical Tm of the DNA sample
Assume a pH of 7.0 in aqueous solution. Please draw a tripeptide containing (in this order) a residue with a residue with an non-polar sidechain containing more than five carbons, a positively (+1) charged sidechain, and a residue with a polar (but not charged) sidechain with more than two carbons. Please give the names of the amino acid residues that you drew.
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Provide the precise chemical description (anomer, isomer, and ring form) of the mono-saccharide subunits that are forming the tri-saccharide sugar molecule. Note the indicated numbering of the carbon atoms for the middle and the right subunit. Research the generic name of the tri-saccharide once you have identified the mono-saccharide subunits. Left subunit: Middle subunit: Right subunit: Name of sugar: b) Provide the precise chemical description of the two bonds that connect the sugar subunits?
A schematic diagram of the helical structure of cytochrome b562 is reproduced below. Thisprotein belongs to the family of -proteins that have a four-helix bundle. Number the helices 1 – 4according to their N  C direction. Indicate relative orientations of the macrodipoles of helices 1 – 4adjacent to the diagram of cytochrome b562. Remember that according to the definition of a dipolethat the arrow points towards the positive end.
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