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- A 30-year-old female patient with uncontrolled hypertension is suspected by an investi- gating endocrinologist of having Conn's syndrome. Results of routine biochemistry were (reference ranges are given in brackets): Sodium Potassium Urea Creatinine Alkaline phosphatase Alanine aminotransferase Albumin Bilirubin Calcium 146 mmol/L 2.1 mmol/L 7.2 mmol/L 146 μmol/L 290 IU/L 20 IU/L 49 g/L 8 μmol/L 2.19 mmol/L (135-145) (3.5-5.0) (3.5-6.6) (70-150) (95-320) (5-42) (35-50) (<17) (2.12-2.62) (a) Are any of the electrolyte concentrations abnormal, and if so what condition is suggested? (b) What further biochemistry investigations would you undertake? Explain your reasoning.In order to avoid increased risk of nephrotoxicity to gentamicin, the minimum concentration during the dosing interval should be allowed to decrease below: Group of answer choices 6 mcg/mL The minimum concentration does not matter, the maximum concentration needs to be greater than 20 mcg/mL to avoid increased risk of nephrotoxicity. 3 mcg/mL 2 mcg/mLa 50-year-old woman with a body mass index in the obese range had a weakness in their muscles. she had a history of increased blood pressure but controlled it with medication. the GP has diagnosed her with extreme hypertension and therefore has given her an increased dosage of blood pressure medication but did not have an effect on her hypertension. the biochemical profile shows: - urea of 8.9 (reference range: 2.5-7.0) - sodium of 162 (reference range: 134-147) - potassium of 2.2 (reference range: 3.5-5.0) -aldosterone of 863 (reference range: 90-700) - renin activity of 4.3 (reference range: 0.5-3.5) - aldosterone/RA ratio of 201 (reference range: <680) -cortisol of 511 (reference range: 138-690) -pH of 7.51 ( reference range : 7.35-7.45) Questions: a)what is the medical condition the patient has and what are the causes? fully explain the rationale which is based on the patients history and the test results indicated above. b)which non invasive test will be taken into…
- Calculate the amount to dispense for each of the following orders. When more than one dosage strength is available, choose the most appropriate. Ordered: Baclofen 5 mg po daily for 60 days On hand: Baclofen 10 mg scored tabletBlood Analysis Glu = 5.0; Na = 145; K = 2.8. Back to patient's chart Glucose Sodium Potassium Calcium Iron Thomas (male) Age: 28 Triage Data complained of abrupt polydipsia (excessive thirst) and polyuria (excessive urine volume, 15 L per day) T3 (triiodothyronine) T4 (thyroxine) 3.9 135 3.5 2.15 Thomas (male) Age: 28 5 0.24 62 Low DII Other Long Description Ca = 2.50 Fe = 27 T3 = 0.33 T4 = 99 glucose urinalysis = 0.0 mmol/L Click here for Report Form NormalThe order is for 1000ml of 5% D/W, 1000ml of Ringers Lactate, 500ml of NS to run over a 36 hour period. The drop factor is 15gtt/ml. How many gtt/min will you administer?Colin who is 78 years old has been admitted to a ward where you are working, with acute bacterial meningitis. The duty doctor wants to treat with meropenem and she would like to know what dose to treat with. In Colin’s notes you see that he has a history of kidney injury, you have his weight which is 49kg and his serum creatinine is 157micromol/L. What is Colin’s estimated creatinine clearance? 2. What is the maximum daily dose (in grams) of meropenem that Colin will receive?Colin who is 78 years old has been admitted to a ward where you are working, with acute bacterial meningitis. The duty doctor wants to treat with meropenem and she would like to know what dose to treat with. In Colin’s notes you see that he has a history of kidney injury, you have his weight which is 49kg and his serum creatinine is 157micromol/L. What is Colin’s estimated creatinine clearance? X([140-age] × weight in kg)/(serum creatinine IN micromol/L Where X =1.04 for female and X= 1.23 for male 2. What is the maximum daily dose (in grams) of meropenem that Colin will receive?None of the above statements is true for medications that are classified as Class Il in the Biopharmaceutical Classification System yet have not yet been given a score of 20? Choose a tenth Low solubility and high permeability are two characteristics that characterise this substance. Low permeability and high solubility are two characteristics of this compound. Permeability and solubility are also strong. Estimation of poor permeability and solubilityAn 84 year old male patient has been given a loading dose of digoxin of 298 micrograms in divided doses by intravenous infusion. He has a creatinine clearance (Ccr) of 34 ml / min. What is the maintenance dose (in micrograms) that this patient should receive? Round your answer to the nearest whole number. Use the formula provided to calculate the maintenance dose. Maintenance Dose = Peak body stores x % daily loss 100 Where: Peak Body Stores = Loading Dose % Daily Loss = 14 + Creatinine clearance (Ccr) 5Give typed full explanation .A child weighing 22 lb is prescribed acetaminophen (Tylenol) every six hours as needed for pain. The dose prescribed is 100 mg. The Nursing Drug Guide states 10–15 mg/kg/dose q4–6h. Do not exceed 5 doses in 24 hours. How much will be administered if the available suspension is 160mg/5mL. Round your answer to the nearest tenth. Is this a safe dose?One general guideline for the maintenance dosing of heparin in pediatric patients is 100 units/kg every4 hours, or 20,000 units/m²/24 hour administered continuously. The a vailable injection for use by intravenous infusion contains 1000 USP Heparin Units/mL For a 44-lb child, measuring 42 inches in height, calculate the difference between the quantities of heparin administered over a 24-hour period in (a) heparin units, (b) in milligrams of heparin (sod ium), and (c) in milliliters of heparin injection.SEE MORE QUESTIONS