for trans-1.2-dichlorocyo 3. The structure below is Formeterol, a long-acting b-adrenergic agonist (LABA) used in combination with inhaled steroids for maintenance therapy in asthma and other respiratory disorders. H OH H Jina H HO Redraw the structure, and label all functional groups by name.
for trans-1.2-dichlorocyo 3. The structure below is Formeterol, a long-acting b-adrenergic agonist (LABA) used in combination with inhaled steroids for maintenance therapy in asthma and other respiratory disorders. H OH H Jina H HO Redraw the structure, and label all functional groups by name.
Introduction to General, Organic and Biochemistry
11th Edition
ISBN:9781285869759
Author:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Publisher:Frederick A. Bettelheim, William H. Brown, Mary K. Campbell, Shawn O. Farrell, Omar Torres
Chapter16: Amines
Section: Chapter Questions
Problem 16.28P: 16-28 Following is the structural formula of metformin, the hydrochloride salt of which is marketed...
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Carbohydrates
Carbohydrates are the organic compounds that are obtained in foods and living matters in the shape of sugars, cellulose, and starch. The general formula of carbohydrates is Cn(H2O)2. The ratio of H and O present in carbohydrates is identical to water.
Starch
Starch is a polysaccharide carbohydrate that belongs to the category of polysaccharide carbohydrates.
Mutarotation
The rotation of a particular structure of the chiral compound because of the epimerization is called mutarotation. It is the repercussion of the ring chain tautomerism. In terms of glucose, this can be defined as the modification in the equilibrium of the α- and β- glucose anomers upon its dissolution in the solvent water. This process is usually seen in the chemistry of carbohydrates.
L Sugar
A chemical compound that is represented with a molecular formula C6H12O6 is called L-(-) sugar. At the carbon’s 5th position, the hydroxyl group is placed to the compound’s left and therefore the sugar is represented as L(-)-sugar. It is capable of rotating the polarized light’s plane in the direction anticlockwise. L isomers are one of the 2 isomers formed by the configurational stereochemistry of the carbohydrates.
Question
Transcribed Image Text:## Understanding the Chemical Structure of Formeterol
### Introduction
Formeterol is a long-acting beta₂-adrenergic agonist (LABA) used primarily in combination with inhaled steroids for maintenance therapy in asthma and other respiratory disorders. Understanding its chemical structure is crucial for comprehending its function and efficacy in medical treatments.
### Structural Details
Below is the chemical structure for Formeterol, which features various functional groups that contribute to its pharmacological activity.
### Functional Groups
**Key Functional Groups in Formeterol's Structure:**
- **Hydroxyl Group** (-OH)
- **Amine Group** (-NH₂)
- **Methoxy Group** (-OCH₃)
- **Carbonyl Group** (C=O)
### Chemical Diagram
The diagram below represents Formeterol’s chemical structure, which includes numerous functional groups:
```image representation of chemical structure```
**Explanation of the Diagram:**
1. **Benzene Ring**: Formeterol contains benzene rings, which are hexagonal shapes representing a ring of carbon atoms with alternating double bonds.
2. **Hydroxyl Group (-OH)**: Located on both benzene rings and the side chain, these groups are highlighted by an oxygen atom bonded to a hydrogen atom, often linked to a carbon atom.
3. **Amine Group (-NH₂)**: Depicted as nitrogen bonded to two hydrogen atoms, typically connected to the carbon chain.
4. **Methoxy Group (-OCH₃)**: Represented by an oxygen atom bonded to a carbon, which in turn is bonded to three hydrogen atoms (for methoxy).
5. **Carbonyl Group (C=O)**: Shown as a carbon atom double-bonded to an oxygen atom, found in the chain of the molecule.
### Practice Exercise
**Redraw the structure, and label all functional groups by name.**
Encouraging students to redraw the structure aids in better understanding and retention of complex chemical structures. Additionally, identifying and labeling each functional group helps in understanding the molecular interactions and potential binding sites relevant for its therapeutic function.
By studying and labeling chemical structures, students can gain a deeper understanding of biochemical processes and pharmaceutical applications.
### Conclusion
Analyzing the structure of Formeterol reveals its complexity and the significant role of functional groups in its activity. This knowledge is essential for those studying pharmacology, medicinal chemistry, and related fields.
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