For the following sequence of reactions you must choose a protecting group (PG', PG, PG) that can withstand the LiBH4 reaction conditions(strong reducing agent, strong nucleophile) and also allow you to remove PG2 in the presence of both PG¹ and PG³. You should provide both thereagents necessary to install the various protecting group as well as to remove PG².HO.NH₂CO₂MeAPG²PG1HO.PG¹HO.PG!NHNHDΝΗCO₂MePG³PG3сBPG2PG²PG1OPG!ΝΗCO₂MeLIBH4strong reducing agent,strong nucleophileNHOH

TBDMS group can be selectively deprotected in the presence of Boc and MOM groups TBDMS and Boc are…

For the following sequence of reactions you must choose a protecting group (PG', PG, PG) that can withstand the LiBH4 reaction conditions (strong reducing agent, strong nucleophile) and also allow you to remove PG2 in the presence of both PG¹ and PG3. You should provide both the reagents necessary to install the various protecting group as well as to remove PG². HO NH₂ CO₂Me A PG2 PG! HO PG! HO PG1 NH NH NH D CO₂Me PG³ PG3 B PG! PG 20 PG! PG₂0 ΝΗ CO₂Me LIBH4 strong reducing agent, strong nucleophile NH OH

For the following sequence of reactions you must choose a protecting group (PG', PG, PG) that can withstand the LiBH4 reaction conditions (strong reducing agent, strong nucleophile) and also allow you to remove PG2 in the presence of both PG¹ and PG3. You should provide both the reagents necessary to install the various protecting group as well as to remove PG². HO NH₂ CO₂Me A PG2 PG! HO PG! HO PG1 NH NH NH D CO₂Me PG³ PG3 B PG! PG 20 PG! PG₂0 ΝΗ CO₂Me LIBH4 strong reducing agent, strong nucleophile NH OH

Chemistry

10th Edition

ISBN:9781305957404

Author:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Publisher:Steven S. Zumdahl, Susan A. Zumdahl, Donald J. DeCoste

Chapter1: Chemical Foundations

Section: Chapter Questions

Problem 1RQ: Define and explain the differences between the following terms. a. law and theory b. theory and...

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