For the following acid-base reaction, identify the correct curved arrow mechanism. of + 00 Na OH I 11 III IV V - H2 + + + + + Na OH e Na OH Na Na e OH e OH + e Na OH H₂O + Na
Reactions of Ethers
Ethers (R-O-R’) are compounds formed by replacing hydrogen atoms of an alcohol (R-OH compound) or a phenol (C6H5OH) by an aryl/ acyl group (functional group after removing single hydrogen from an aromatic ring). In this section, reaction, preparation and behavior of ethers are discussed in the context of organic chemistry.
Epoxides
Epoxides are a special class of cyclic ethers which are an important functional group in organic chemistry and generate reactive centers due to their unusual high reactivity. Due to their high reactivity, epoxides are considered to be toxic and mutagenic.
Williamson Ether Synthesis
An organic reaction in which an organohalide and a deprotonated alcohol forms ether is known as Williamson ether synthesis. Alexander Williamson developed the Williamson ether synthesis in 1850. The formation of ether in this synthesis is an SN2 reaction.
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For the following acid-base reaction, identify the correct curved arrow mechanism.
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O no, the resulting conjugate base would have a localized negative on a carbon atom where NaNH₂ has a negative on the more
electronegative nitrogen atom
O
no, there are no acidic protons attached to the oxygen atoms
O no, NaNH₂ produces NH3 when protonated which then will leave the reaction mixture
O yes, the resulting conjugate base would have delocalization of charge over two oxygen atoms, whereas NaNH₂ has a
localized negative charge.
O yes, as NaNH₂ has only two hydrogen atoms attached to the nitrogen atom, and the compound has eight total hydrogen
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